Clinical characteristics and outcomes of COVID-19 in patients with type 2 diabetes in Turkey: A nationwide study (TurCoviDia)

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dc.authoridDemirci, Ibrahim/0000-0003-0498-3115
dc.authoridSatman, Ilhan/0000-0001-8613-1797
dc.authoridTASCI, ILKER/0000-0002-0936-2476
dc.authoridDagdelen, Selcuk/0000-0002-0513-1750
dc.authoridsahin, mustafa/0000-0002-4718-0083
dc.authoridSonmez, Alper/0000-0002-9309-7715
dc.authoridcelik, osman/0000-0003-2131-2866
dc.authorwosidsalman, serpil/GRX-8413-2022
dc.authorwosidDemirci, Ibrahim/AAR-3277-2020
dc.authorwosidŞahin, İbrahim/HHY-8303-2022
dc.authorwosidCelik, Osman/KLZ-6766-2024
dc.authorwosidSatman, Ilhan/AAS-7044-2020
dc.authorwosidTASCI, ILKER/B-7556-2009
dc.authorwosidDagdelen, Selcuk/A-9432-2017
dc.contributor.authorSonmez, Alper
dc.contributor.authorDemirci, Ibrahim
dc.contributor.authorHaymana, Cem
dc.contributor.authorTasci, Ilker
dc.contributor.authorDagdelen, Selcuk
dc.contributor.authorSalman, Serpil
dc.contributor.authorAta, Naim
dc.date.accessioned2024-08-04T20:49:25Z
dc.date.available2024-08-04T20:49:25Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground Coronavirus disease 2019 (COVID-19) has been reported to be associated with a more severe course in patients with type 2 diabetes mellitus (T2DM). However, severe adverse outcomes are not recorded in all patients. In this study, we assessed disease outcomes in patients with and without T2DM hospitalized for COVID-19. Methods A nationwide retrospective cohort of patients with T2DM hospitalized with confirmed COVID-19 infection from 11 March to 30 May 2020 in the Turkish Ministry of Health database was investigated. Multivariate modeling was used to assess the independent predictors of demographic and clinical characteristics with mortality, length of hospital stay, and intensive care unit (ICU) admission and/or mechanical ventilation. Results A total of 18 426 inpatients (median age [interquartile range, IQR]: 61 [17] years; males: 43.3%) were investigated. Patients with T2DM (n = 9213) were compared with a group without diabetes (n = 9213) that were matched using the propensity scores for age and gender. Compared with the group without T2DM, 30-day mortality following hospitalization was higher in patients with T2DM (13.6% vs 8.7%; hazard ratio 1.75; 95% CI, 1.58-1.93; P < .001). The independent associates of mortality were older age, male gender, obesity, insulin treatment, low lymphocyte count, and pulmonary involvement on admission. Older age, low lymphocyte values, and pulmonary involvement at baseline were independently associated with longer hospital stay and/or ICU admission. Conclusions The current study from the Turkish national health care database showed that patients with T2DM hospitalized for COVID-19 are at increased risk of mortality, longer hospital stay, and ICU admission.en_US
dc.identifier.doi10.1111/1753-0407.13171
dc.identifier.endpage595en_US
dc.identifier.issn1753-0393
dc.identifier.issn1753-0407
dc.identifier.issue7en_US
dc.identifier.pmid33655669en_US
dc.identifier.scopus2-s2.0-85102931455en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage585en_US
dc.identifier.urihttps://doi.org/10.1111/1753-0407.13171
dc.identifier.urihttps://hdl.handle.net/11616/99843
dc.identifier.volume13en_US
dc.identifier.wosWOS:000632185100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal of Diabetesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCOVID-19en_US
dc.subjecthospital stayen_US
dc.subjectintensive care unit admissionen_US
dc.subjectmortalityen_US
dc.subjecttype 2 diabetesen_US
dc.titleClinical characteristics and outcomes of COVID-19 in patients with type 2 diabetes in Turkey: A nationwide study (TurCoviDia)en_US
dc.typeArticleen_US

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