Right-Lobe Living-Donor Liver Transplantation in Adult Patients With Acute Liver Failure

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dc.authoridhatipoglu, sinan/0000-0002-4423-084X
dc.authoridYILMAZ, Mehmet/0000-0002-5710-5263
dc.authoridAtes, Mustafa/0000-0003-2821-453X
dc.authoridince, volkan/0000-0002-0714-490X
dc.authoridIsik, Burak/0000-0002-2395-3985
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authorwosidhatipoglu, sinan/V-9137-2017
dc.authorwosidYILMAZ, Mehmet/HKM-4739-2023
dc.authorwosidAtes, Mustafa/ABI-5100-2020
dc.authorwosidince, volkan/M-7325-2017
dc.authorwosidYilmaz, Mehmet/AAF-6095-2021
dc.authorwosidIsik, Burak/A-6657-2018
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.contributor.authorAtes, M.
dc.contributor.authorHatipoglu, S.
dc.contributor.authorDirican, A.
dc.contributor.authorIsik, B.
dc.contributor.authorInce, V.
dc.contributor.authorYilmaz, M.
dc.contributor.authorAydin, C.
dc.date.accessioned2024-08-04T20:37:41Z
dc.date.available2024-08-04T20:37:41Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.descriptionBerlin Symposium on Xenotransplantation / 24th International Congress of the Transplantation-Society (TTS) -- JUL 13-19, 2012 -- Robert Koch Inst, Berlin, GERMANYen_US
dc.description.abstractBackground. Right-lobe living-donor liver transplantation (RLDLT) is an excellent option to reduce donor shortages for adult patients with acute liver failure (ALF). The aim of this study was to evaluate the etiologies and outcomes of 30 consecutive adult patients who underwent emergency RLDLT for ALP. Methods. Between January 2007 and September 2011, we examined data from medical records of patients with ALF who underwent RLDLT. Results. Their mean age was 32.2 +/- 13.05 years. The etiologies of ALP were acute hepatitis B (n = 11; 36.6%), hepatitis A (n = 4; 13.3%), drug intoxication (n = 4; 13.3%), pregnancy (n = 2; 6.7%), hepatitis B with pregnancy (n = 1; 3.3%), mushroom intoxication (n = 1; 3.3%), and unknown (n = 7; 23.3%). The mean hepatic coma grade (Model for End-Stage Liver Disease score) was 34.13 +/- 8.72. The 43 (48.7%) postoperative complications were minor (grades I-II) and 44 (51.3%) were major (grades III-V). Reoperation was required in 14 of 30 (47%) recipients (grades IIIb-IVa). Deaths occurred owing to pulmonary (n = 2), cardiac (n = 1), septic (n = 2), or encephalopathic (n = 4) complications. The mean durations of intensive care unit stay and postoperative hospitalization were 3.2 +/- 2.3 and 29.5 +/- 23 days, respectively. The survival rate was 70%. The mean follow-up duration was 305 days (range, 1-1582). Conclusion. Liver transplantation is potentially the only curative modality, markedly improving the prognosis of patients with ALP. The interval between ALF onset and death is short and crucial because of the rapid, progressive multiorgan failure. Thus, RLDLT should be considered to be a life-saving procedure for adult patients with ALF, requiring quicker access to a deceased-donor liver graft and a short ischemia time.en_US
dc.description.sponsorshipTransplantat Soc,Int Xenotransplantat Assocen_US
dc.identifier.doi10.1016/j.transproceed.2012.10.056
dc.identifier.endpage1952en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue5en_US
dc.identifier.pmid23769080en_US
dc.identifier.scopus2-s2.0-84879201241en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1948en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2012.10.056
dc.identifier.urihttps://hdl.handle.net/11616/96103
dc.identifier.volume45en_US
dc.identifier.wosWOS:000321316500059en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFulminant Hepatic-Failureen_US
dc.subjectComplicationsen_US
dc.subjectExperienceen_US
dc.titleRight-Lobe Living-Donor Liver Transplantation in Adult Patients With Acute Liver Failureen_US
dc.typeConference Objecten_US

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