Auditory changes in acromegaly

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dc.authoridHatipoglu, Esra/0000-0001-8361-8866
dc.authoridAkarsu, Ersin/0000-0003-2786-6616
dc.authoridHatipoglu, Esra/0000-0001-8361-8866
dc.authorwosidHatipoglu, Esra/ABI-7268-2020
dc.authorwosidbaysal, elif/AAH-6406-2019
dc.authorwosidAkarsu, Ersin/AAH-4325-2020
dc.authorwosidHatipoglu, Esra/I-1793-2013
dc.contributor.authorTabur, S.
dc.contributor.authorKorkmaz, H.
dc.contributor.authorBaysal, E.
dc.contributor.authorHatipoglu, E.
dc.contributor.authorAytac, I.
dc.contributor.authorAkarsu, E.
dc.date.accessioned2024-08-04T20:43:10Z
dc.date.available2024-08-04T20:43:10Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective The aim of this study is to determine the changes involving auditory system in cases with acromegaly. Materials and methods Otological examinations of 41 cases with acromegaly (uncontrolled n = 22, controlled n = 19) were compared with those of age and gender-matched 24 healthy subjects. Whereas the cases with acromegaly underwent examination with pure tone audiometry (PTA), speech audiometry for speech discrimination (SD), tympanometry, stapedius reflex evaluation and otoacoustic emission tests, the control group did only have otological examination and PTA. Additionally, previously performed paranasal sinus-computed tomography of all cases with acromegaly and control subjects were obtained to measure the length of internal acoustic canal (IAC). Results PTA values were higher (p < 0.001 for right ears and p = 0.001 for left ears), and SD scores were (p = 0.002 for right ears and p = 0.002 for left ears) lower in acromegalic patients. IAC width in acromegaly group was narrower compared to that in control group (p = 0.03 for right ears and p = 0.02 for left ears). When only cases with acromegaly were taken into consideration, PTA values in left ears had positive correlation with growth hormone and insulin-like growth factor-1 levels (r = 0.4, p = 0.02 and r = 0.3, p = 0.03). Of all cases with acromegaly 13 (32%) had hearing loss in at least one ear, 7 (54%) had sensorineural type and 6 (46%) had conductive type hearing loss. Conclusion Acromegaly may cause certain changes in the auditory system in cases with acromegaly. The changes in the auditory system may be multifactorial causing both conductive and sensorioneural defects.en_US
dc.identifier.doi10.1007/s40618-016-0602-x
dc.identifier.endpage626en_US
dc.identifier.issn1720-8386
dc.identifier.issue6en_US
dc.identifier.pmid28035526en_US
dc.identifier.scopus2-s2.0-85019110514en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage621en_US
dc.identifier.urihttps://doi.org/10.1007/s40618-016-0602-x
dc.identifier.urihttps://hdl.handle.net/11616/97812
dc.identifier.volume40en_US
dc.identifier.wosWOS:000402073400007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofJournal of Endocrinological Investigationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcromegalyen_US
dc.subjectAuditoryen_US
dc.subjectHearingen_US
dc.titleAuditory changes in acromegalyen_US
dc.typeArticleen_US

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