The Platelet Parameters as Inflammatory Markers in Preschool Children with Atopic Eczema

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dc.authoridtopal, erdem/0000-0002-4439-2689
dc.authorwosidCeliksoy, Mehmet Halil/A-3889-2015
dc.authorwosidtopal, erdem/ABI-7545-2020
dc.contributor.authorTopal, Erdem
dc.contributor.authorCeliksoy, Mehmet Halil
dc.contributor.authorCatal, Ferhat
dc.contributor.authorKarakoc, Habib Tadayyon Einaddin
dc.contributor.authorKaradag, Ahmet
dc.contributor.authorSancak, Recep
dc.date.accessioned2024-08-04T20:40:19Z
dc.date.available2024-08-04T20:40:19Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground: Mean platelet volume has been frequently used as an inflammatory marker in various diseases associated with inflammation. In this study, we compared platelet parameter levels between preschool children with and without atopic eczema (AE). Methods: Preschool children with AE and age-matched healthy children were included in the study. Complete blood count was assessed in children with AE while platelet parameters were compared between children with and without AE. Results: One hundred twenty eight pediatric patients (78 boys, mean age: 14 months) diagnosed with AE and 128 healthy patients (71 boys, mean age: 12 months) were included in the study. There were no statistically significant differences between the genders (p = 0.375) and ages (p = 0.273) of both groups. WBC (p = 0.952), Hb (p = 0.370), MCV (p = 0.314) and RDW values (p = 0.124), and platelet counts (p = 0.198) of both groups were similar. In the AE group, while the MPV value was found to be higher (p = 0.003), mean PDW value (p = 0.025) and PLT/MPV ratio were found to be lower (p = 0.021). In addition, there was no correlation between the severity of AE and MPV (rho; 0.1, p = 0.257), POW (rho; -0.1, p = 0.269) and PLT/MPV (rho; 0.07, p = 0.432) ratio. Conclusions: In patients with AE, as a sign of inflammation, PDW value and PLT/MPV ratio decrease while MPV value increases. This study has also shown that there is no association between the severity of AE and platelet parameters.en_US
dc.identifier.doi10.7754/Clin.Lab.2014.140930
dc.identifier.endpage496en_US
dc.identifier.issn1433-6510
dc.identifier.issue5-6en_US
dc.identifier.pmid26118181en_US
dc.identifier.scopus2-s2.0-84934272026en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage493en_US
dc.identifier.urihttps://doi.org/10.7754/Clin.Lab.2014.140930
dc.identifier.urihttps://hdl.handle.net/11616/96853
dc.identifier.volume61en_US
dc.identifier.wosWOS:000355782000008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherClin Lab Publen_US
dc.relation.ispartofClinical Laboratoryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectatopic eczemaen_US
dc.subjectinflammationen_US
dc.subjectmean platelet volumeen_US
dc.subjectplatelet parametersen_US
dc.subjectseverityen_US
dc.titleThe Platelet Parameters as Inflammatory Markers in Preschool Children with Atopic Eczemaen_US
dc.typeArticleen_US

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