Prognostic markers in operated non-small cell lung cancer patients

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dc.contributor.authorCırık, Salih
dc.contributor.authorHarputluoğlu, Hakan
dc.date.accessioned2024-08-04T19:42:44Z
dc.date.available2024-08-04T19:42:44Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: The overall survival (OS) of operable lung cancer patients is directly related to clinicopathological features and some laboratory parameters. In this study, we aimed to examine the factors affecting the survival of the operated patients. Materials and Methods: In our study, we retrospectively analyzed 202 operated-on patients diagnosed with lung carcinoma who were in stages I–IIIA at the time of diagnosis. The clinico-pathological features and some laboratory parameters of the patients included in our study were retrospectively analyzed. The effects of those parameters on the overall survival of the patients and their disease-free survival (DFS) have been investigated. Results: The age of the patient at the time of diagnosis and the presence of lymphovascular invasion (LVI) were found to be statistically significant in terms of OS (p<0.05). Pathological tumor size, LVI, and peri-neural invasion (PNI) parameters were statistically significant for DFS. In addition, neutrophil-lymphocyte ratio (NLR), which is an inflammatory indicator, is an important parameter with statistical significance in terms of both OS and DFS (p<0.05). Conclusion: Our study yielded that LVI and PNI parameters would be beneficial to estimate patients’ survival and prognosis. In addition, NLR was observed to have a statistically significant effect on OS and DFS.en_US
dc.identifier.doi10.5455/annalsmedres.2023.09.252
dc.identifier.endpage1494en_US
dc.identifier.issn2636-7688
dc.identifier.issue12en_US
dc.identifier.startpage1487en_US
dc.identifier.trdizinid1215009en_US
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2023.09.252
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1215009
dc.identifier.urihttps://hdl.handle.net/11616/88635
dc.identifier.volume30en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titlePrognostic markers in operated non-small cell lung cancer patientsen_US
dc.typeArticleen_US

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