Association of fibrinogen and C-reactive protein with severity of preeclampsia

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dc.authoridEngin-Ustun, Yaprak/0000-0002-1011-3848
dc.authorwosidUstun, Yaprak/KFQ-9767-2024
dc.authorwosidÜstün, Yusuf/AAC-2674-2020
dc.contributor.authorÜstün, Y
dc.contributor.authorEngin-Üstün, Y
dc.contributor.authorKamaci, M
dc.date.accessioned2024-08-04T20:14:53Z
dc.date.available2024-08-04T20:14:53Z
dc.date.issued2005
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to determine the levels of plasma fibrinogen and C-reactive protein (CRP) in preeclampsia and their association with the severity of the disease. Study design: CRP and plasma levels of fibrinogen were investigated in 26 cases of normal pregnant women, 26 cases with mild preeclampsia and 26 cases with severe preeclampsia in the third trimester of pregnancy. Mean arterial pressure (MAP) was used as an indicator of the severity of the disease. Analysis of variance with the Kruskal-Wallis test was used when three groups were compared. For correlations, Spearman's rank correlation tests were used. A receiver operating characteristic curve was constructed to evaluate the sensitivity and specificity of CRP. Results: Plasma CRP and fibrinogen levels in mild and severe preeclampsia patients were markedly higher than that of normal third trimester pregnant women. There were significant correlations between MAP and CRP (r = 0.515, p = 0.0001) and MAP and fibrinogen parameters (r = 0.383, p = 6.005) in pregnancies complicated with preeclampsia. Conclusion: We found higher levels of fibrinogen and CRP and presence of good correlation between CRP and MAP in preeclampsia. (c) 2004 Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ejogrb.2004.12.009
dc.identifier.endpage158en_US
dc.identifier.issn0301-2115
dc.identifier.issue2en_US
dc.identifier.pmid16054955en_US
dc.identifier.scopus2-s2.0-23044493645en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage154en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2004.12.009
dc.identifier.urihttps://hdl.handle.net/11616/94028
dc.identifier.volume121en_US
dc.identifier.wosWOS:000231354300005en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofEuropean Journal of Obstetrics Gynecology and Reproductive Biologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectpreeclampsiaen_US
dc.subjectC-reactive proteinen_US
dc.subjectfibrinogenen_US
dc.subjectseverity of diseaseen_US
dc.titleAssociation of fibrinogen and C-reactive protein with severity of preeclampsiaen_US
dc.typeArticleen_US

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