Prevalence of the helicobacter pylori in the tonsils and adenoids
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Brazilian Journal of Otorhinolaryngology
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Introduction: There is an ongoing debate about the existence and effects of Helicobacter pylori
(Hp) in adenotonsillar tissue.
Objective: A clinical study was conducted to assess the existence of Hp in the adenoid and/or
adenotonsillar tissues, which were surgically excised due to chronic adenotonsillitis.
Methods: Phosphoglucosamine mutase gene for the detection of Hp and cytotoxin-associated
gene as virulence gene were examined in 84 adenotonsillar tissues obtained from 64 patients
and patients’ serum by using polymerase chain reaction.
Results: Hp IgG was detected in 57 (89%) patients’ serum. A total of seven tissue samples
from 64 patients (10.9%) were found positive for Hp DNA, of which five were adenoids and two
were tonsil tissues. All polymerase chain reaction positive samples were also positive for the
cytotoxin-associated gene, which is a virulence determinant for the organism.
Conclusion: This study suggests that children are exposed to Hp at an early age of their life in
this province. Hp may have a role in the pathogenesis of chronic adenotonsillitis, especially in
endemic areas.
© 2015 Associac¸ão Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by
Elsevier Editora Ltda. All rights reserved.
Açıklama
Anahtar Kelimeler
Helicobacter pylori, Reservoirs, Adenoids, Palatine tonsil
Kaynak
Brazilian Journal of Otorhinolaryngology
WoS Q Değeri
Scopus Q Değeri
Cilt
81
Sayı
3
Künye
Bayındır, T. Toplu, Y. Otlu, B. Yakupoğulları, Y. Yıldırım, Ö. Kalcıoğlu, M. T. (2015). Prevalence of the Helicobacter pylori in the tonsils and adenoids. Brazilian Journal of Otorhinolaryngology, 81(3), 307–311.
