Prevalence of the helicobacter pylori in the tonsils and adenoids

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dc.authorid101949en_US
dc.contributor.authorBayındır, Tuba
dc.contributor.authorToplu, Yüksel
dc.contributor.authorOtlu, Barış
dc.contributor.authorYakupoğulları, Yusuf
dc.contributor.authorYıldırım, Özge
dc.contributor.authorKalcıoğlu, Mahmut Tayyar
dc.date.accessioned2017-07-10T08:07:23Z
dc.date.available2017-07-10T08:07:23Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: There is an ongoing debate about the existence and effects of Helicobacter pylori (Hp) in adenotonsillar tissue. Objective: A clinical study was conducted to assess the existence of Hp in the adenoid and/or adenotonsillar tissues, which were surgically excised due to chronic adenotonsillitis. Methods: Phosphoglucosamine mutase gene for the detection of Hp and cytotoxin-associated gene as virulence gene were examined in 84 adenotonsillar tissues obtained from 64 patients and patients’ serum by using polymerase chain reaction. Results: Hp IgG was detected in 57 (89%) patients’ serum. A total of seven tissue samples from 64 patients (10.9%) were found positive for Hp DNA, of which five were adenoids and two were tonsil tissues. All polymerase chain reaction positive samples were also positive for the cytotoxin-associated gene, which is a virulence determinant for the organism. Conclusion: This study suggests that children are exposed to Hp at an early age of their life in this province. Hp may have a role in the pathogenesis of chronic adenotonsillitis, especially in endemic areas. © 2015 Associac¸ão Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.en_US
dc.identifier.citationBayındır, T. Toplu, Y. Otlu, B. Yakupoğulları, Y. Yıldırım, Ö. Kalcıoğlu, M. T. (2015). Prevalence of the Helicobacter pylori in the tonsils and adenoids. Brazilian Journal of Otorhinolaryngology, 81(3), 307–311.en_US
dc.identifier.doi10.1016/j.bjorl.2014.08.018en_US
dc.identifier.endpage311en_US
dc.identifier.issn18088694
dc.identifier.issue3en_US
dc.identifier.startpage307en_US
dc.identifier.urihttp://linkinghub.elsevier.com/retrieve/pii/S1808869415000440
dc.identifier.urihttps://hdl.handle.net/11616/7355
dc.identifier.volume81en_US
dc.language.isoenen_US
dc.publisherBrazilian Journal of Otorhinolaryngologyen_US
dc.relation.ispartofBrazilian Journal of Otorhinolaryngologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHelicobacter pylorien_US
dc.subjectReservoirsen_US
dc.subjectAdenoidsen_US
dc.subjectPalatine tonsilen_US
dc.titlePrevalence of the helicobacter pylori in the tonsils and adenoidsen_US
dc.typeArticleen_US

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