Antimicrobial, Antioxidant, and Antityrosinase Activities of Morina persica L. and Its Isolated Compounds

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dc.contributor.authorOzgen, Ridvan
dc.contributor.authorKaraoglan, Esen Sezen
dc.contributor.authorSevindik, Handan Gokben
dc.contributor.authorHanci, Hayrunisa
dc.contributor.authorKazaz, Cavit
dc.date.accessioned2024-08-04T20:56:12Z
dc.date.available2024-08-04T20:56:12Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, the isolation of compounds from the aerial parts of Morina persica L. and the antimicrobial, antioxidant and antityrosinase activities of various polarity extracts and isolated compounds were investigated. Column chromatography methods were used for isolation. A microdilution method was used to determine antimicrobial activity; Folin-Ciocalteu method was used to determine total phenolic content; DPPH and ABTS radical scavenging- capacity methods were used to determine antioxidant activity; and a mushroom tyrosinase method was used to determine antityrosinase activity. Kaempferol-3-O-beta-glucopyranoside (astragalin) and quercetin-3-O-rutinoside (rutin) were isolated from M. persica. The extracts and compounds showed higher activity against Staphylococcus aureus and Enterococcus faecalis than other tested bacteria. The highest phenolic content, DPPH, and ABTS radical scavenging activity were detected in an ethyl acetate extract at 50 mu g/mL concentration. The methanol extract showed the highest antityrosinase effect at 200 mu g/mL concentration.en_US
dc.description.sponsorshipAtatuerk University Scientific Research Projects Coordination Office (BAP) [TYL-2023-11978]en_US
dc.description.sponsorshipThis study was financially supported by Atatuerk University Scientific Research Projects Coordination Office (BAP; Project No: TYL-2023-11978).en_US
dc.identifier.doi10.3390/molecules29133017
dc.identifier.issn1420-3049
dc.identifier.issue13en_US
dc.identifier.pmid38998969en_US
dc.identifier.scopus2-s2.0-85198437121en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.3390/molecules29133017
dc.identifier.urihttps://hdl.handle.net/11616/102116
dc.identifier.volume29en_US
dc.identifier.wosWOS:001266760200001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.ispartofMoleculesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMorina persica L.en_US
dc.subjectantimicrobialen_US
dc.subjectantioxidanten_US
dc.subjectantityrosinaseen_US
dc.titleAntimicrobial, Antioxidant, and Antityrosinase Activities of Morina persica L. and Its Isolated Compoundsen_US
dc.typeArticleen_US

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