Simultaneous use of continuous veno-venous hemodiafiltration and activated protein C for treatment of septic shock and acute renal failure (case report)

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dc.authorscopusid7004621949
dc.authorscopusid6603245381
dc.authorscopusid6603402358
dc.authorscopusid55898201200
dc.authorscopusid7004486274
dc.contributor.authorÇiçek M.
dc.contributor.authorGedik E.
dc.contributor.authorDo?an Z.
dc.contributor.authorGülhaş N.
dc.contributor.authorErsoy M.Ö.
dc.date.accessioned2024-08-04T20:00:56Z
dc.date.available2024-08-04T20:00:56Z
dc.date.issued2006
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The mortality of severe sepsis and septic shock is extremely high. We aimed to present a case to which we applicated continuous veno-venous hemodiafiltration and activated protein C for treatment of septic shock and acute renal failure. Case report: Assessment of the 42 -year old male with gun-shot wound in the emergency service revealed that Glasgow Coma Scale 3, isochoric pupils, bilateral positive light reflex, cold and pale skin, spontaneous ventilation rate (38 min-1), blood pressure (64/42 mmHg), and heart rate (174 min-1). In urgent operation, primary repair of liver laceration and diaphragm rupture, cholecystectomy, caecum resection and ileocolostomy, greft to femoral artery, thorax drainage with bilateral tubes, orchiectomy and debridment of tibia fracture were performed. After the operation, he was mechanically ventilated in intensive care unit. In first day, APACHE II score was determined as 34. In the 9th day, septic shock and acute renal failure developed in spite of antibacterial and supportive treatments. In another operation, subhepatic abscess drainage, repair of ileocolic anastomosis and ileostomy were performed. Activated protein C and continuous veno-venous hemodiafiltration were started following the operation. Activated protein C treatment was stopped for 2 hours and than percutaneous tracheotomy was performed. Activated protein C was started again one hour after the tracheotomy and than administered totally 96 hours. Patient was discharged with tibia fracture sequel in the 47th day. Conclusion: In a case with septic shock and acute renal failure due to abdominal infection, in addition to standard care and treatment of cause of sepsis, simultaneous continuous veno-venous hemodiafiltration application and activated protein C administration may be life-saving.en_US
dc.identifier.endpage119en_US
dc.identifier.issn1300-0578
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-33745899599en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage116en_US
dc.identifier.urihttps://hdl.handle.net/11616/91134
dc.identifier.volume14en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofAnestezi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectActivated protein Cen_US
dc.subjectAcute renal failureen_US
dc.subjectContinuous veno-venous hemodiafiltrationen_US
dc.subjectSeptic shocken_US
dc.titleSimultaneous use of continuous veno-venous hemodiafiltration and activated protein C for treatment of septic shock and acute renal failure (case report)en_US
dc.title.alternativeSepti?k Şok ve Akut Böbrek Yetmezli??i?Tedavi??inde Eş Zamanli Devamli Veno-Venöz Hemodi?yafi?ltrasyon ve Ak?ive Protei?n C Kullanimi (Olgu Sunumu)en_US
dc.typeArticleen_US

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