Evaluation of salivary total oxidant-antioxidant status and DNA damage of children undergoing fixed orthodontic therapy
dc.authorid | Guler, Cigdem/0000-0002-2581-9050 | |
dc.authorid | Otlu, Onder/0000-0001-5958-7609 | |
dc.authorwosid | Guler, Cigdem/KPA-0490-2024 | |
dc.authorwosid | Otlu, Onder/W-3887-2018 | |
dc.contributor.author | Guler, Cigdem | |
dc.contributor.author | Toy, Ebubekir | |
dc.contributor.author | Ozturk, Firat | |
dc.contributor.author | Gunes, Dilek | |
dc.contributor.author | Karabulut, Aysun Bay | |
dc.contributor.author | Otlu, Onder | |
dc.date.accessioned | 2024-08-04T20:40:07Z | |
dc.date.available | 2024-08-04T20:40:07Z | |
dc.date.issued | 2015 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description.abstract | Objective: To determine the total oxidant status (TOS), total antioxidant status (TAS), and the 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels and their interrelationship in the saliva of children undergoing fixed orthodontic therapy. Materials and Methods: Thirty children were randomly divided into three groups. The attachments were bonded to all of the teeth using three different orthodontic composites: Transbond XT, Kurasper F, and GrenGloo. The salivary levels of TOS, TAS, and 8-OHdG were determined three times, as follows: before treatment (T-1) and at 1 month (T-2) and 3 months (T-3) following appliance placement. All data were statistically analyzed. Results: There were no significant differences in TOS, TAS, and 8-OHdG within the same time periods among the three different orthodontic composites (P > .05). TAS in all composite groups decreased over time. These decreases were found to be significant for Kurasper F and GrenGloo at the T1 T3 and T2 T3 time periods (P < .05). In all composite groups 8-OHdG decreased between T1 and T2 (P < .05). However, 8-OHdG in all composite groups increased from T2 to T3. These differences in 8-OHdG were significant in Kurasper F and GrenGloo (P < .05). Conclusions: Fixed orthodontic appliances bonded with the tested composites did not increase the cytotoxicity markers in saliva. | en_US |
dc.identifier.doi | 10.2319/110113-798.1 | |
dc.identifier.endpage | 244 | en_US |
dc.identifier.issn | 0003-3219 | |
dc.identifier.issn | 1945-7103 | |
dc.identifier.issue | 2 | en_US |
dc.identifier.pmid | 24949910 | en_US |
dc.identifier.scopus | 2-s2.0-84924865802 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | 239 | en_US |
dc.identifier.uri | https://doi.org/10.2319/110113-798.1 | |
dc.identifier.uri | https://hdl.handle.net/11616/96709 | |
dc.identifier.volume | 85 | en_US |
dc.identifier.wos | WOS:000350531200010 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | E H Angle Education Research Foundation, Inc | en_US |
dc.relation.ispartof | Angle Orthodontist | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Total oxidant status | en_US |
dc.subject | Total antioxidant status | en_US |
dc.subject | 8-Hydroxy-2 '-deoxyguanosine | en_US |
dc.title | Evaluation of salivary total oxidant-antioxidant status and DNA damage of children undergoing fixed orthodontic therapy | en_US |
dc.type | Article | en_US |