Cytotoxic effects of resin-modified orthodontic band adhesives Are they safe?

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dc.authoridSENGUN, Abdulkadir/0000-0002-6053-160X
dc.contributor.authorMalkoc, Siddik
dc.contributor.authorCorekci, Bayram
dc.contributor.authorBotsali, Hayriye Esra
dc.contributor.authorYalcin, Muhammet
dc.contributor.authorSengun, Abduelkadir
dc.date.accessioned2024-08-04T20:32:31Z
dc.date.available2024-08-04T20:32:31Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To evaluate the cytotoxic effects of three different resin-modified orthodontic band adhesives. Materials and Methods: Three resin-modified orthodontic band adhesives (Bisco Ortho Band Paste LC (TM), Multi-Cure Glass lonomer Band Cement (TM), and Transbond Plus Light Cure Band Adhesive (TM)) were prepared and the samples were extracted in 3 mL of Basal Medium Eagle with 10% newborn calf serum for 24 hours. The L929 cells were plated (25,000 cells/mL) in wells of 96-well dishes and maintained in a humidified incubator for 24 hours at 37 degrees C, 5% CO(2), and 95% air. After 24-hour incubation of the cells, the incubation medium was replaced by the immersed medium in which the samples were stored. Then L929 cells were incubated in contact with eluates for 24 hours. The cell mitochondrial activity was evaluated by the methyltetrazolium test. Twelve wells were used for each specimen, and methyltetrazolium tests were applied two times. The data were statistically analyzed using one-way analysis of variance and Tukey Honestly Significantly Different tests. Results: Results with L929 fibroblasts demonstrated that all freshly prepared resin-modified orthodontic band adhesive materials reduced vital cell numbers (P > .05), in comparison to the control group. Our data demonstrate that all materials showed significant cytotoxicity compared to the control group. Conclusions: The results indicate that all materials showed significant cytotoxicity compared to the control group, and further studies using different test methods are needed for all resin-modified orthodontic band adhesives. (Angle Orthod. 2010;80:890-895.)en_US
dc.identifier.doi10.2319/101509-577.1
dc.identifier.endpage895en_US
dc.identifier.issn0003-3219
dc.identifier.issue5en_US
dc.identifier.pmid20578860en_US
dc.identifier.scopus2-s2.0-77955614687en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage890en_US
dc.identifier.urihttps://doi.org/10.2319/101509-577.1
dc.identifier.urihttps://hdl.handle.net/11616/95106
dc.identifier.volume80en_US
dc.identifier.wosWOS:000281471900014en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE H Angle Education Research Foundation, Incen_US
dc.relation.ispartofAngle Orthodontisten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiocompatibilityen_US
dc.subjectOrthodontic band adhesiveen_US
dc.subjectCytotoxicityen_US
dc.titleCytotoxic effects of resin-modified orthodontic band adhesives Are they safe?en_US
dc.typeArticleen_US

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