Portosystemic Shunts for Too Small-for-Size Syndrome After Liver Transplantation: A Systematic Review

dc.authoridKınacı, Erdem/0000-0002-0380-7585;
dc.authorwosidKınacı, Erdem/HTR-1780-2023
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.contributor.authorKinaci, Erdem
dc.contributor.authorKayaalp, Cuneyt
dc.date.accessioned2024-08-04T20:41:45Z
dc.date.available2024-08-04T20:41:45Z
dc.date.issued2016
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPortosystemic shunts (PSSs) modulate the portal hyperperfusion against small-for-size syndrome (SFSS) after split or living donor liver transplantation. To find out the results and the limitations of PSSs against SFSS. We searched PubMed and Cochrane databanks for systematic review and analyzed the indications, types, morbidities, and survivals of the PSSs at split or living donor liver transplantations. Total 66 patients were assessed in 16 studies. Main indications for PSS were graft recipient weight ratio (GRWRs) < 0.8 % and/or portal vein pressure > 20 mmHg. Five different types of PSSs were described but hemi-portocaval shunts were the most common one. The incidence of SFSS was 12 %. Overall 90-day, 1-, and 3-year graft survivals were 80, 70, and 47 %, respectively. GRWR < 0.65 % was found as the only significant parameter on graft survival. The 90-day, 1- and 3-year graft survivals for GRWR < 0.65 and a parts per thousand yen0.65 % patients were 62.5, 42.8, and 30.0 and 95, 94, and 67 %, respectively (p = 0.03, p = 0.01, and p = 0.18). PSSs can modulate the small graft size (GRWR < 0.8 %) and/or portal hypertension (> 20 mmHg) after split or living donor liver transplantations sufficiently. However, its protective effect is not unlimited. If the GRWR is below 0.65 %, survival decreases significantly despite PSSs.en_US
dc.identifier.doi10.1007/s00268-016-3518-x
dc.identifier.endpage1940en_US
dc.identifier.issn0364-2313
dc.identifier.issn1432-2323
dc.identifier.issue8en_US
dc.identifier.pmid27160453en_US
dc.identifier.scopus2-s2.0-84966605859en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1932en_US
dc.identifier.urihttps://doi.org/10.1007/s00268-016-3518-x
dc.identifier.urihttps://hdl.handle.net/11616/97315
dc.identifier.volume40en_US
dc.identifier.wosWOS:000380054000017en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofWorld Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSingle-Center Experienceen_US
dc.subjectPortal Venous-Pressureen_US
dc.subjectLeft Renal-Veinen_US
dc.subjectPortacaval-Shunten_US
dc.subjectLeft Lobeen_US
dc.subjectClinical-Implicationsen_US
dc.subjectInflow Modulationen_US
dc.subjectLiving Donorsen_US
dc.subjectWeight Ratioen_US
dc.subjectGraften_US
dc.titlePortosystemic Shunts for Too Small-for-Size Syndrome After Liver Transplantation: A Systematic Reviewen_US
dc.typeReview Articleen_US

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