Assessment of the Effects of Quince Seed Mucilage and Wheat Germ Oil on Wound Healing in Rats

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dc.authoridSelcuk, Aysu/0000-0001-6424-7457
dc.authoridCULHA, CANAN/0000-0002-7714-7444
dc.authorwosidSelcuk, Aysu/JNS-9690-2023
dc.contributor.authorCulha, Canan
dc.contributor.authorGun, Zeynep Ulku
dc.contributor.authorSelcuk, Aysu
dc.contributor.authorApikoglu, Sule
dc.date.accessioned2024-08-04T20:11:42Z
dc.date.available2024-08-04T20:11:42Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: People have used traditional herbal medicines for wound care since the dawn of time. This study aimed to assess the cutaneous wound healing effects of wheat germ oil (WGO) and quince seed mucilage (QSM) in rats. Methods: Adult female Wistar albino rats were allocated to one of the three groups: rats treated with topical WGO (n=6); topical QSM (n=6); and topical saline (n=6) as the control group. Two circular, full-thickness wounds of 0.6 mm diameter were created on the dorsal thoracic region of each rat. Test and control solutions were applied twice daily for 14 days. Wound healing was assessed by measuring the wound contraction rate and the time needed for complete epithelialization. Results: When compared with the control group, rats in the WGO group had reduced wound closure rates in the first four days, but considerably greater rates in the 8th, 10th, and 12th days, as well as a shorter duration of time needed to complete epithelialization (11 days vs. 13 days). The wound closure rates of the rats in the QSM group were not substantially different from the control rats and the duration of time needed for complete epithelialization was not significantly different from the control group. Conclusion: WGO use has been shown to improve wound healing. It may be used as an alternative or complementary approach for wound treatment depending on the severity of the wounds. On the other hand, QSM was not found to improve wound healing.en_US
dc.identifier.doi10.33808/clinexphealthsci.1112790
dc.identifier.endpage561en_US
dc.identifier.issn2459-1459
dc.identifier.issue3en_US
dc.identifier.startpage555en_US
dc.identifier.trdizinid1196407en_US
dc.identifier.urihttps://doi.org/10.33808/clinexphealthsci.1112790
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1196407
dc.identifier.urihttps://hdl.handle.net/11616/92941
dc.identifier.volume13en_US
dc.identifier.wosWOS:001153376600017en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherMarmara Univ, Inst Health Sciencesen_US
dc.relation.ispartofClinical and Experimental Health Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectWound healingen_US
dc.subjectwheat germ oilen_US
dc.subjectquince seed mucilageen_US
dc.titleAssessment of the Effects of Quince Seed Mucilage and Wheat Germ Oil on Wound Healing in Ratsen_US
dc.typeArticleen_US

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