Comparison of the effects of Argon and Neodymium: YAG laser iridotomy on cytokines in the rabbit aqueous humor

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dc.authoridTürköz, Yusuf/0000-0001-5401-0720
dc.authoridGündüz, Abuzer/0000-0003-1752-6810
dc.authoridözyalın, fatma/0000-0001-6486-6389
dc.authoridÖzyalın, Fatma/0000-0001-6486-6389
dc.authorwosidEvereklioğlu, Cem/A-5370-2018
dc.authorwosidTürköz, Yusuf/ABG-7931-2020
dc.authorwosidGündüz, Abuzer/HLH-2417-2023
dc.authorwosidözyalın, fatma/ABA-5258-2020
dc.authorwosidÖzyalın, Fatma/ABC-7193-2020
dc.contributor.authorEr, H
dc.contributor.authorDoganay, S
dc.contributor.authorEvereklioglu, C
dc.contributor.authorTurkoz, Y
dc.contributor.authorGündüz, A
dc.contributor.authorBorazan, M
dc.contributor.authorOzyalin, F
dc.date.accessioned2024-08-04T20:12:19Z
dc.date.available2024-08-04T20:12:19Z
dc.date.issued2002
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPURPOSE. We compared the effects in rabbits of iridotomy using the argon or Nd:YAG laser on cytokines such as interleukin 1-beta (IL-1beta), interleukin 6 (IL-6), interleukin 8 (IL-8), and tumor necrosis factor-alpha (TNF-alpha). METHODS. Twenty pigmented rabbits (20 eyes) underwent argon and Nd:YAG iridotomy under general and topical anesthesia. Group 1 (10 right eyes) was treated with the argon laser and group 2 (10 right eyes) with the Nd:YAG laser, using an equal number of shots and the same laser parameters for each group. Left eyes in both groups were evaluated as controls. Aqueous humor specimens were collected from each eye preoperatively and 1 and 3 days postoperatively. RESULTS. Aqueous IL-6 and TNF-a levels rose more on day 1 in the Nd:YAG group than the argon group. IL-6 and TNF-a levels were significantly higher on days 1 and 3 than the pre-operative and control levels (p<0.05). TNF-alpha levels on day 1 were significantly lower in the Nd:YAG than the argon group. There were no significant differences between the two laser groups for IL-6 on days 1 and 3. IL-1beta and IL-8 did not change CONCLUSIONS. Our findings suggest that cytokines, particularly IL-6 and TNF-alpha, may be inflammatory mediators in the early inflammation following argon and Nd:YAG laser iridotomies. These results also indicate that cytokines contribute to the acute effects of Nd:YAG and argon laser applications on inflammation.en_US
dc.identifier.doi10.1177/112067210201200302
dc.identifier.endpage187en_US
dc.identifier.issn1120-6721
dc.identifier.issue3en_US
dc.identifier.pmid12113562en_US
dc.identifier.scopus2-s2.0-0035987023en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage183en_US
dc.identifier.urihttps://doi.org/10.1177/112067210201200302
dc.identifier.urihttps://hdl.handle.net/11616/93366
dc.identifier.volume12en_US
dc.identifier.wosWOS:000176677100003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWichtig Editoreen_US
dc.relation.ispartofEuropean Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectArgon laseren_US
dc.subjectNeodymium : YAG laseren_US
dc.subjectiridotomyen_US
dc.subjectcytokinesen_US
dc.subjectaqueous humoren_US
dc.titleComparison of the effects of Argon and Neodymium: YAG laser iridotomy on cytokines in the rabbit aqueous humoren_US
dc.typeArticleen_US

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