Comparison of antioxidant enzyme activity in the internal spermatic vein and brachial veins of patients with infertile varicocele

Basit Öğe Kaydı
dc.authoridTürköz, Yusuf/0000-0001-5401-0720;
dc.authorwosidcekmen, mustafa baki/G-6122-2011
dc.authorwosidTürköz, Yusuf/ABG-7931-2020
dc.authorwosidSoylu, Ahmet/P-2015-2019
dc.contributor.authorOzbek, Emin
dc.contributor.authorCekmen, Mustafa
dc.contributor.authorSimsek, Abdulmuttalip
dc.contributor.authorTurkoz, Yusuf
dc.contributor.authorSoylu, Ahmet
dc.contributor.authorIlbey, Y. Ozlem
dc.contributor.authorBalbay, M. Derya
dc.date.accessioned2024-08-04T20:30:56Z
dc.date.available2024-08-04T20:30:56Z
dc.date.issued2008
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim Recent studies have shown that both oxidative and reductive stresses are present within the internal spermatic vein of patients with varicocele. The aim of this study was to compare the activities of antioxidant enzymes in the internal spermatic vein and brachial vein of patients with varicocele. Methods Fifteen primary infertile varicocele patients and ten normal-nonvaricocele-fertile control subjects participated in this study. The patients and subjects were first given a physical and color doppler examination, and then whole blood samples were drawn from the brachial vein and a dilated internal spermatic vein during surgery. Superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) enzyme activities were assessed by enzymatic methods, and the results were compared using the Mann-Whitney U test. Results The activity of SOD in the internal spermatic veins and brachial veins of patients with varicocele was 60.17 +/- 2.15 and 42.10 +/- 1.60 U/g protein, respectively; that of GSH-Px was 5.44 +/- 0.14 and 3.92 +/- 0.14 U/g protein, respectively. The results were statistically significant (P < 0.05). In the control group, the activity of SOD in the internal spermatic veins and brachial veins was 43.12 +/- 1.80 and 40.01 +/- 2.10 U/g protein, respectively; that of GSH-Px was 3.35 +/- 0.20 and 3.7 +/- 0.10 U/g protein, respectively (P > 0.05). Conclusions Increased antioxidant enzyme activity in the internal spermatic vein may be due to increased oxidative stress in the internal spermatic vein: the increase in antioxidant enzyme activity may be a response to offset the toxic actions of reactive oxygen species. Further studies are needed to confirm this suggestion.en_US
dc.identifier.doi10.1007/s11255-008-9339-6
dc.identifier.endpage683en_US
dc.identifier.issn0301-1623
dc.identifier.issue3en_US
dc.identifier.pmid18264794en_US
dc.identifier.scopus2-s2.0-48549087411en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage679en_US
dc.identifier.urihttps://doi.org/10.1007/s11255-008-9339-6
dc.identifier.urihttps://hdl.handle.net/11616/94610
dc.identifier.volume40en_US
dc.identifier.wosWOS:000258063200023en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Urology and Nephrologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantioxidant enzyme activityen_US
dc.subjectglutathione peroxidaseen_US
dc.subjectinfertilityen_US
dc.subjectsuperoxide dismutaseen_US
dc.subjectvaricoceleen_US
dc.titleComparison of antioxidant enzyme activity in the internal spermatic vein and brachial veins of patients with infertile varicoceleen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu