Memory impairment in patients with cirrhosis
Küçük Resim Yok
Tarih
2005
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Natl Med Assoc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background and Aim: Subdinical hepatic encephalopathy (HE) in cirrhotic patients is usually characterized by memory impairment and psychomotor slowing. Our aim was to investigate memory status in cirrhotic patients with and without clinically overt HE. Material and Methods: Thirty-two cirrhotic patients (10 female and 22 male) aged 49 17 years and 20 healthy subjects (six female and 14 male) aged 46 12 years were included in the study. Memory status was defined by Wechsler Memory Scale, verbal memory process and complex memory process tests. Results: Grade-1 HE was detected in 7 (22%) patients with cirrhosis. We detected 36 to 92% decrement in various memory tests in cirrhotic patients without HE as compared to healthy subjects. The scores for all psychometric testing results were significantly lower in cirrhotic patients without HE as compared to healthy subjects. We detected 42.9 to 100% decrement in various memory tests in cirrhotic patients with HE than cirrhotic patients without HE. However, there was no statistical significant difference between cirrhotic patients with and without HE. There was no statistical significant difference in cirrhotic patients with Child-Pugh A, B, and C. Conclusion: In conclusion, memory status was influenced in which patients with cirrhosis yet has a normal mental and neurological status to routine clinical examination (subclinical HE). Occasionally, decreased memory performance may adversely affect the satisfaction and lifestyle of these patients. Therefore, subclinical HE is an important social problem.
Açıklama
Anahtar Kelimeler
cirrhosis, subclinical hepatic encephalopathy, psychometric tests, memory
Kaynak
Journal of The National Medical Association
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
97
Sayı
2
