In vitro antioxidant and antimicrobial assays of acetone extracts from Nepeta meyeri Bentham

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dc.authoridAkgoz, Muslum/0000-0001-5065-8087
dc.authoridCigremis, Yilmaz/0000-0002-8600-0946
dc.authoridAkgoz, Muslum/0000-0001-5065-8087
dc.authorwosidAkgoz, Muslum/A-6234-2015
dc.authorwosidCigremis, Yilmaz/JAC-8451-2023
dc.authorwosidCigremis, Yilmaz/O-6019-2015
dc.authorwosidAkgoz, Muslum/AAG-4598-2019
dc.contributor.authorCigremis, Y.
dc.contributor.authorUlukanli, Z.
dc.contributor.authorIlcim, A.
dc.contributor.authorAkgoz, M.
dc.date.accessioned2024-08-04T20:32:31Z
dc.date.available2024-08-04T20:32:31Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground and Objectivies: Nepeta species are used as diuretic, diaphoretic, antitussive, antispasmodic, antiasthmatic, febrifuge, emmenagogue, sedative agents, insecticidal, acaricidal, antiviral, anti-inflammatory and antioxidant. Acetone extract of Nepeta meyeri (Labiatae) was screened for antioxidant and antimicrobial activities. Materials and Methods: The antioxidant properties of the extract were investigated by using various methods established in vitro systems such as 1,1-diphenyl-2-picrylhydrazyl (DPPH)/nitric oxide (NO) radical scavenging activity. Reducing power and total phenolic substance analysis and also antimicrobial activity of acetone extract of Nepeta meyeri were tested against six gram negative, seven gram positive bacteria and the yeast strain using the disc diffusion method. Results and Discussion: Acetone extract of the plant examined exhibited a significant concentration-dependent inhibition of DPPH and NO center dot radical. Furthermore, Nepeta meyeri showed very high reducing power. In DPPH radical and NO center dot scavenging assays the IC50 value of extract was 672.2 mu g/ml and 165.32 mu g/ml, respectively. The amounts of total phenolic compounds were also determined and 12.86 mu g pyrocatechol equivalents of phenols were detected in the extract. The data obtained from these in vitro models clearly demonstrated antioxidant potential of acetone extract of Nepeta meyeri. The extract revealed antibacterial activity against all gram positive bacteria but not was active against gram negative bacteria.en_US
dc.identifier.endpage668en_US
dc.identifier.issn1128-3602
dc.identifier.issue8en_US
dc.identifier.pmid20707285en_US
dc.identifier.scopus2-s2.0-77955966648en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage661en_US
dc.identifier.urihttps://hdl.handle.net/11616/95111
dc.identifier.volume14en_US
dc.identifier.wosWOS:000280836000002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherVerduci Publisheren_US
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNepeta meyerien_US
dc.subjectLamiaceaeen_US
dc.subjectAntimicrobial activityen_US
dc.subjectDPPHen_US
dc.subjectNOen_US
dc.subjectAntioxidant activityen_US
dc.titleIn vitro antioxidant and antimicrobial assays of acetone extracts from Nepeta meyeri Benthamen_US
dc.typeArticleen_US

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