Effect of partially hydrolyzed synbiotic formula milk on weight gain of late preterm and term infants-a multicenter study

Basit Öğe Kaydı
dc.authoridSahin, Suzan/0000-0002-2599-3075
dc.authoridDeveci, Mehmet Fatih/0000-0002-3328-4156
dc.authoridOncel, Mehmet Yekta/0000-0003-0760-0773
dc.authoridAKCAN, ABDULLAH/0000-0003-0181-1166
dc.authorwosidSahin, Suzan/AGE-6338-2022
dc.authorwosidDeveci, Mehmet Fatih/IYS-3534-2023
dc.authorwosidOncel, Mehmet Yekta/L-5664-2013
dc.authorwosidAKCAN, ABDULLAH/Q-3855-2019
dc.contributor.authorSahin, Suzan
dc.contributor.authorBuyuktiryaki, Mehmet
dc.contributor.authorOkur, Nilufer
dc.contributor.authorAkcan, Abdullah Baris
dc.contributor.authorDeveci, Mehmet Fatih
dc.contributor.authorYurttutan, Sadik
dc.contributor.authorGunes, Sezgin
dc.date.accessioned2024-08-04T20:54:48Z
dc.date.available2024-08-04T20:54:48Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Data on the effectiveness of hydrolyzed infant formula containing both pre- and probiotics (synbiotic formula) on the growth of infants is still scarce. This retrospective study was designed to evaluate the effect of a partially hydrolyzed synbiotic formula on growth parameters and the possible occurrence of major gastrointestinal adverse events or morbidities in infants born via cesarean section (C-section) delivery.Methods: C-section-delivered term and late preterm infants who received either partially hydrolyzed synbiotic formula, standard formula, or maternal milk and followed at seven different hospitals from five different regions of Turkey, during a 1-year period with a minimum follow-up duration of 3 months were evaluated retrospectively. All the included infants were evaluated for their growth patterns and any kind of morbidity such as diarrhea, constipation, vomiting, infection, or history of hospitalization.Results: A total of 198 infants (73 in the human milk group, 61 in the standard formula group, and 64 in the partially hydrolyzed synbiotic formula group) reached the final analysis. The groups were similar regarding their demographic and perinatal characteristics. No difference was observed between the three groups regarding gastrointestinal major side effects. Growth velocities of the infants in the human milk and partially hydrolyzed synbiotic formula groups during the first month of life were similar whereas the weight gain of infants in the standard formula group was significantly less than these two groups (p < 0.001). Growth velocities were similar among the three groups between 1st and 3rd months of age.Discussion: A partially hydrolyzed synbiotic formula provided better weight gain in late-preterm and term infants who were delivered via C-section delivery compared to the standard formula during the first month of life. This weight gain was similar to the infants receiving exclusively human milk. This difference was not observed in length and head circumference gain. No difference was observed in any of the parameters during the 1st-3rd months of age. Specially formulated partially hydrolyzed synbiotic formulas may reverse at least some of the negative impacts of C-section delivery on the infant and help to provide better growth, especially during the early periods of life.en_US
dc.description.sponsorshipThe author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.en_US
dc.description.sponsorshipThe author(s) declare that no financial support was received for the research, authorship, and/or publication of this article.en_US
dc.identifier.doi10.3389/fped.2023.1270442
dc.identifier.issn2296-2360
dc.identifier.pmid37928348en_US
dc.identifier.scopus2-s2.0-85175805751en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.3389/fped.2023.1270442
dc.identifier.urihttps://hdl.handle.net/11616/101653
dc.identifier.volume11en_US
dc.identifier.wosWOS:001096535500001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherFrontiers Media Saen_US
dc.relation.ispartofFrontiers in Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectsynbiotic formulaen_US
dc.subjectpartially hydrolyzed formulaen_US
dc.subjectinfant growthen_US
dc.subjectformula toleranceen_US
dc.subjectside effecten_US
dc.titleEffect of partially hydrolyzed synbiotic formula milk on weight gain of late preterm and term infants-a multicenter studyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu