Electrochemical determination of N-acetyl cysteine in the presence of acetaminophen at multi-walled carbon nanotubes and nafion modified sensor

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dc.authoridKuyumcu Savan, Ebru/0000-0002-8851-0907
dc.authorwosidKuyumcu Savan, Ebru/E-3430-2019
dc.contributor.authorSavan, Ebru Kuyumcu
dc.date.accessioned2024-08-04T20:45:32Z
dc.date.available2024-08-04T20:45:32Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, an electrochemical sensor was used for simultaneously determination of N-acetyl cysteine (NAC) and acetaminophen (AC) using differential pulse voltammetry. Modification on the surface of a glassy carbon electrode (GCE) was carried out using multi-walled carbon nanotubes (MWCNTs) and Nafion (NF). The morphology and structure of the MWCNT-NF nanocomposites were characterised by scanning electron microscopy (SEM). The modified sensor showed excellent performance for the oxidation reactions of NAC and AC. Using the modified sensor, the oxidation peak potentials of NAC and AC were separated by a potential difference of 350 mV, while they were coincident at the bare electrode. Moreover, the current densities were significantly improved using the modified sensor. The modified sensor displayed a linear response range of 20-500 mu M NAC and the detection limit was 0.43 mu M (S/N = 3). Under optimal conditions, the modified sensor exhibited excellent stability and selectivity, with high precision and accuracy. With the satisfactory results obtained from the real samples analysis, the modified sensor can be used for routine analysis. To the best of our knowledge, this is the first study in the literature that detected NAC in the presence of AC at GCE/MWCNT-NF modified sensor.en_US
dc.identifier.doi10.1016/j.snb.2018.11.092
dc.identifier.endpage506en_US
dc.identifier.issn0925-4005
dc.identifier.scopus2-s2.0-85057065879en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage500en_US
dc.identifier.urihttps://doi.org/10.1016/j.snb.2018.11.092
dc.identifier.urihttps://hdl.handle.net/11616/98542
dc.identifier.volume282en_US
dc.identifier.wosWOS:000455090000059en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Saen_US
dc.relation.ispartofSensors and Actuators B-Chemicalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectN-Acetyl cysteineen_US
dc.subjectAcetaminophenen_US
dc.subjectMulti-walled carbon nanotubesen_US
dc.subjectElectrochemical sensoren_US
dc.titleElectrochemical determination of N-acetyl cysteine in the presence of acetaminophen at multi-walled carbon nanotubes and nafion modified sensoren_US
dc.typeArticleen_US

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