Protective effect of myricetin against e2-induced genotoxic damage in human lymphocytes

Basit Öğe Kaydı
dc.authorscopusid12797912000
dc.authorscopusid55565378700
dc.authorscopusid55217816900
dc.authorscopusid55218229500
dc.authorscopusid55217816300
dc.contributor.authorYuksel S.
dc.contributor.authorYesilada E.
dc.contributor.authorGulbay G.
dc.contributor.authorKurtoglu E.
dc.contributor.authorSerap Savaci S.
dc.date.accessioned2024-08-04T20:00:39Z
dc.date.available2024-08-04T20:00:39Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractProtective effect of myricetin (MRY) against the cytotoxic and genotoxic effects of a hormonal steroid, 17 ßestradiol (E2), was assessed in peripheral blood human lymphocyte culture. Sister chromatid exchanges (SCE), mitotic index (MI) and replication index (RI) were scored as genetic endpoints. Firstly, the genotoxic effect of different amounts (5, 10 and 20 ?M final concentration) of E2 was tested, and 10 and 20 ?M E2 levels were detected as genotoxic. In the second set, E2 groups were treated with 10 ?M MRY. MRY reduced the SCE but increased MI as well as RI, suggesting its protective action on human lymphocytes in vitro against E2-induced genotoxic damage. © by PSP.en_US
dc.identifier.endpage1026en_US
dc.identifier.issn1018-4619
dc.identifier.issue4 Aen_US
dc.identifier.scopus2-s2.0-84861059499en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1022en_US
dc.identifier.urihttps://hdl.handle.net/11616/90905
dc.identifier.volume21en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofFresenius Environmental Bulletinen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEstradiolen_US
dc.subjectGenotoxicityen_US
dc.subjectHuman lymphocytesen_US
dc.subjectMyricetinen_US
dc.titleProtective effect of myricetin against e2-induced genotoxic damage in human lymphocytesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

Scopus İndeksli Yayınlar Koleksiyonu