EFFECT OF PHYSICAL ACTIVITY ON PLASMA ADRENOMEDULLIN CONCENTRATION AND ITS RELATIONSHIP WITH NITRIC OXIDE IN ATHLETES

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dc.authoridDursun, Nurcan/0000-0001-7560-216X
dc.authoridYurekli, Muhittin/0000-0002-5830-8564
dc.authorwosidDursun, Nurcan/AAT-6485-2021
dc.authorwosidÖzdoğan, Kalender/F-2439-2014
dc.authorwosidYurekli, Muhittin/B-4414-2016
dc.contributor.authorDursun, Nurcan
dc.contributor.authorYurekli, Muhittin
dc.contributor.authorOzdogan, Kalender
dc.date.accessioned2024-08-04T20:35:53Z
dc.date.available2024-08-04T20:35:53Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to determine whether regular physical activity or acute exercise influenced plasma adrenomedullin (AM) concentration and whether it was related to gender, blood pressure and nitric oxide (NO) production. Material and Methods: Sixty healthy students participated in this study. They were divided into two groups. The first group consisted of 30 students, 16 female, 14 male athletes carrying out regular exercise. The second group was made up of 15 females, 15 males nonathletes. All students submitted to a cycle exercise test until volitional exhaustion. Heart rate (HR), blood pressure, maximal oxygen uptake (VO2 max) and carbon dioxide production (VCO2) were measured continously. Before starting, at the 1st min and at the 30th min of exercise, venous blood samples were taken to determine AM and NO production. Results: AM in the female and male athletes were significantly higher than in the female and male non-athletes. The plasma AM concentration in female athletes was found be significantly higher than in male athletes. Acute exercise did not affect AM concentration in subjects. We did not find any relationship between AM/BMI (Body mass index) and other variables such as systolic, diastolic pressure, heart rate, VO2 max and VCO2 but there was a negative relationship with NO production. Conclusion: The present data suggest that an increase in AM during prolonged physical activity may be a compensatory mechanism against further elevation of blood pressure.en_US
dc.description.sponsorshipErciyes University Foundation [ID: 2107]en_US
dc.description.sponsorshipThis study was funded by the Erciyes University Foundation (ID: 2107). The authors thank Dr. Nihayet Mehmet Bayraktar for measurement of nitric oxide.en_US
dc.identifier.doi10.5152/etd.2012.01
dc.identifier.endpage6en_US
dc.identifier.issn2149-2247
dc.identifier.issn2149-2549
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84861174099en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1en_US
dc.identifier.urihttps://doi.org/10.5152/etd.2012.01
dc.identifier.urihttps://hdl.handle.net/11616/95658
dc.identifier.volume34en_US
dc.identifier.wosWOS:000421216500002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofErciyes Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdrenomedullinen_US
dc.subjectBlood Pressureen_US
dc.subjectExerciseen_US
dc.subjectOxygen Consumptionen_US
dc.titleEFFECT OF PHYSICAL ACTIVITY ON PLASMA ADRENOMEDULLIN CONCENTRATION AND ITS RELATIONSHIP WITH NITRIC OXIDE IN ATHLETESen_US
dc.typeArticleen_US

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