Futility Versus Acceptability of the Use of Grafts Taken From End of Line in the National Organ-Sharing Network

dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridsoyer, haci vural/0000-0003-4271-7467
dc.authoridYologlu, Saim/0000-0002-9619-3462
dc.authoridSARICI, KEMAL BARIŞ/0000-0001-9595-1906
dc.authoridIsik, Burak/0000-0002-2395-3985
dc.authoridKayaalp, Cuneyt/0000-0003-4657-2998
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidsoyer, haci vural/KAM-0073-2024
dc.authorwosidYologlu, Saim/ABI-8014-2020
dc.authorwosidSARICI, KEMAL BARIŞ/ABI-4356-2020
dc.authorwosidIsik, Burak/A-6657-2018
dc.authorwosidKayaalp, Cuneyt/AAH-1764-2021
dc.contributor.authorSoyer, V.
dc.contributor.authorKoc, S.
dc.contributor.authorOnur, A.
dc.contributor.authorSarici, B.
dc.contributor.authorKayaalp, C.
dc.contributor.authorIsik, B.
dc.contributor.authorUnal, B.
dc.date.accessioned2024-08-04T20:40:18Z
dc.date.available2024-08-04T20:40:18Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. The number of suitable donors for organ transplantation is limited in many countries. This limitation can be overcome with the use of organs removed from marginal donors (expanded-criteria donors [ECDs]). We examined the long-term results of 187 patients who underwent marginal cadaveric liver transplantation in our institution. Methods. The data of patients who underwent cadaveric liver transplantation from January 2007 to April 2014 were retrospectively reviewed. ECDs were evaluated by considering 19 internationally accepted criteria. The clinical data of recipients including age, clinical status, and Model for End-Stage Liver Disease (MELD) score were also assessed. Results. A total of 287 patients underwent cadaveric liver transplantation. A graft from an ECD was used in 181 (63.06%) patients. The mean MELD score was 18.8. In all, 45 patients (24.86%) underwent transplantations for fulminant liver failure and 136 patients (75.14%) underwent transplantations for other chronic conditions. The majority of donors died of cerebrovascular disease and trauma. Only hypotension requiring inotropic drugs and obesity significantly affected survival. The 90-day and 12-month survival rates of the recipients who received a graft from an ECD were 51.93% and 46.2%, respectively. Conclusions. The use of ECD allografts immediately and significantly expands the existing donor pool. Because of persistent organ scarcity, pressure to use a greater proportion of the existing donor pool will continue to increase.en_US
dc.identifier.doi10.1016/j.transproceed.2015.04.067
dc.identifier.endpage1261en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue5en_US
dc.identifier.pmid26093693en_US
dc.identifier.scopus2-s2.0-84931357934en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1257en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2015.04.067
dc.identifier.urihttps://hdl.handle.net/11616/96829
dc.identifier.volume47en_US
dc.identifier.wosWOS:000357066800004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSingle-Center Experienceen_US
dc.subjectExtended Donor Criteriaen_US
dc.subjectLiver-Transplantationen_US
dc.subjectMarginal Donorsen_US
dc.subjectPopulationen_US
dc.subjectAcceptanceen_US
dc.subjectMalignancyen_US
dc.subjectImpacten_US
dc.subjectRisken_US
dc.subjectPoolen_US
dc.titleFutility Versus Acceptability of the Use of Grafts Taken From End of Line in the National Organ-Sharing Networken_US
dc.typeArticleen_US

Dosyalar