Effects of Organic Apricot on Liver Regeneration After Partial Hepatectomy in Rats

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dc.authoridTaşlidere, Aslı Cetin/0000-0003-3902-3210
dc.authoridVardı, Nigar/0000-0003-0576-1696
dc.authoridYilmaz, Ismet/0000-0001-8680-3098;
dc.authorwosidTaşlidere, Aslı Cetin/AAB-3979-2021
dc.authorwosidVardı, Nigar/C-9549-2018
dc.authorwosidYilmaz, Ismet/H-4144-2019
dc.authorwosidKARAMAN, Abdurrahman/G-7825-2016
dc.authorwosidYılmaz, ismet/AAG-8946-2019
dc.contributor.authorYilmaz, I.
dc.contributor.authorKaraman, A.
dc.contributor.authorVardi, N.
dc.contributor.authorCetin, A.
dc.contributor.authorErdemli, E.
dc.date.accessioned2024-08-04T20:37:46Z
dc.date.available2024-08-04T20:37:46Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground. The present study investigated the effects of (sun-dried organic apricot/SDOA) supplementation in chow on liver regeneration after partial hepatectomy/(PH) in rats. Method. In this study, 28 female rats were randomized into four groups. On the 7th day of the study, group 1 underwent laparoscopic intervention while a PH was performed on the other three cohorts. On day 28, all rats were humanely killed. Blood and liver tissue samples were subjected to biochemical determinations, histological examinations, and measurement of tissue oxidative stress enzyme activity. Results. Serum levels of alanine transaminase (ALT), alkaline phosphatase (ALP), and liver tissue glutathione (GSH) activities were affected by PH and/or SDOA consumption (P < .05). Moderately staining cell counts in group 4 were significantly different from the other three groups (P < .05). However, no significant differences were detected among all groups in regard to aspartate aminotransferase (AST) serum levels or liver tissue superoxide dismutase (SOD), malondialdehyde (MDA), catalase (CAT) or glutathione peroxidase (GSHpx) activities (P < .05). Conclusion. The 5% SDOA supplementation over a 21-day feeding period showed a beneficial effect on liver regeneration in rats, as reflects by Ki-67 finding although there was no change in ALT or ALP or in liver tissue GSH activity.en_US
dc.description.sponsorshipScientific Research Fund of Inonu University [2010/152]; Unit of Scientific Research Projects of Inonu Universityen_US
dc.description.sponsorshipSupported by the Scientific Research Fund of Inonu University (project no. 2010/152) and the Unit of Scientific Research Projects of Inonu University.en_US
dc.identifier.doi10.1016/j.transproceed.2013.04.005
dc.identifier.endpage2460en_US
dc.identifier.issn0041-1345
dc.identifier.issn1873-2623
dc.identifier.issue6en_US
dc.identifier.pmid23953562en_US
dc.identifier.scopus2-s2.0-84882271053en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage2455en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2013.04.005
dc.identifier.urihttps://hdl.handle.net/11616/96175
dc.identifier.volume45en_US
dc.identifier.wosWOS:000323852000068en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBiochemical Parametersen_US
dc.subjectOxidative Stressen_US
dc.subjectVitamin-Een_US
dc.subjectInjuryen_US
dc.titleEffects of Organic Apricot on Liver Regeneration After Partial Hepatectomy in Ratsen_US
dc.typeArticleen_US

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