Chondroradionecrosis in two patients with laryngeal carcinoma

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dc.authorscopusid55924315300
dc.authorscopusid6603956791
dc.authorscopusid58385279200
dc.authorscopusid7004027424
dc.authorscopusid6603777920
dc.contributor.authorFirat Y.
dc.contributor.authorKizilay A.
dc.contributor.authorFirat A.K.
dc.contributor.authorSerin M.
dc.contributor.authorErkal H.S.
dc.date.accessioned2024-08-04T20:01:08Z
dc.date.available2024-08-04T20:01:08Z
dc.date.issued2007
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPostradiotherapy necrosis in the larynx is a rare but serious complication. It must be differentiated from tumor recurrence with radiological and histopathological studies. Herein, we presented two patients with stage II and stage IV larynx carcinoma who developed chondroradionecrosis following radiotherapy. The first patient did not accept surgical treatment and was treated with curative radiotherapy at a dose of 70 Gy. The other one received adjuvant radiotherapy at a dose of 46 Gy following total laryngectomy and bilateral functional neck dissection. The two patients were evaluated with computed tomography and magnetic resonance imaging, respectively. Pathologic examination of multiple biopsies taken from both cases showed coagulation necrosis without malignancy. The first patient had grade IV radionecrosis according to the Chandler classification and underwent total laryngectomy because of non-functional larynx. Histopathologically, there were no malignant cells, but widespread fibrosis and coagulation necrosis. The other patient was treated with conservative treatment and local debridement.en_US
dc.identifier.endpage248en_US
dc.identifier.issn1300-7475
dc.identifier.issue4en_US
dc.identifier.pmid18187981en_US
dc.identifier.scopus2-s2.0-40949107904en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage242en_US
dc.identifier.urihttps://hdl.handle.net/11616/91281
dc.identifier.volume17en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.relation.ispartofKulak burun bo?az ihtisas dergisi : KBB = Journal of ear, nose, and throaten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectageden_US
dc.subjectarticleen_US
dc.subjectcase reporten_US
dc.subjectcomputer assisted tomographyen_US
dc.subjectdifferential diagnosisen_US
dc.subjecthumanen_US
dc.subjectlarynxen_US
dc.subjectlarynx tumoren_US
dc.subjectmaleen_US
dc.subjectmiddle ageden_US
dc.subjectmultimodality cancer therapyen_US
dc.subjectnecrosisen_US
dc.subjectnuclear magnetic resonance imagingen_US
dc.subjectpathologyen_US
dc.subjectradiation injuryen_US
dc.subjectAgeden_US
dc.subjectCombined Modality Therapyen_US
dc.subjectDiagnosis, Differentialen_US
dc.subjectHumansen_US
dc.subjectLaryngeal Neoplasmsen_US
dc.subjectLarynxen_US
dc.subjectMagnetic Resonance Imagingen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectNecrosisen_US
dc.subjectRadiation Injuriesen_US
dc.subjectTomography, X-Ray Computeden_US
dc.titleChondroradionecrosis in two patients with laryngeal carcinomaen_US
dc.title.alternativeLarenks karsinomlu iki hastada kondroradyonekroz.en_US
dc.typeArticleen_US

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