Random-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cycles

Basit Öğe Kaydı
dc.authoridOzturk, Banu/0000-0003-0290-8787
dc.authoridTURKCUOGLU, ILGIN/0000-0002-8342-1956
dc.authoridSonmezer, Murat/0000-0001-6101-1414
dc.authorwosidOzturk, Banu/AAD-4358-2019
dc.authorwosidSonmezer, Murat/AAI-8964-2020
dc.contributor.authorSonmezer, Murat
dc.contributor.authorTurkcuoglu, Ilgin
dc.contributor.authorCoskun, Ugur
dc.contributor.authorOktay, Kutluk
dc.date.accessioned2024-08-04T20:32:49Z
dc.date.available2024-08-04T20:32:49Z
dc.date.issued2011
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To report an emergency approach of random-start controlled ovarian hyperstimulation (COH) in the late follicular or luteal phase of the menstrual cycle for embryo cryopreservation in patients with cancer. Design: Case series. Setting: Academic tertiary referral centers. Patient(s): Three patients with a diagnosis of breast cancer requiring emergency fertility preservation in the late follicular or luteal phase of the menstrual cycle. Intervention(s): After baseline pelvic ultrasound and hormonal evaluation, random-start COH was commenced immediately on menstrual cycle days 11, 14, or 17 with use of letrozole 2.5 mg/d and recombinant FSH 150 to 300 IU/d. Gonadotropin-releasing hormone antagonist was administered to prevent ovulation in all cases. Ovulation was triggered with either 250 mu g of recombinant hCG or 10,000 IU of urinary hCG. Main Outcome Measure(s): Number of oocytes harvested, maturity and fertilization rates, number of embryos frozen. Result(s): Nine to 17 oocytes were harvested, resulting in the freezing of seven to 10 embryos with the mean maturity and fertilization rates of 58.8% to 77.7% and 69.2% to 87.5%, respectively. Conclusion(s): In an emergent setting, ovarian stimulation can be started at a random cycle date for the purpose of fertility preservation without compromising fertilization rates in letrozole cycles. (Fertil Steril (R) 2011;95: 2125.e9-e11. (C) 2011 by American Society for Reproductive Medicine.)en_US
dc.identifier.doi10.1016/j.fertnstert.2011.01.030
dc.identifier.issn0015-0282
dc.identifier.issn1556-5653
dc.identifier.issue6en_US
dc.identifier.pmid21292255en_US
dc.identifier.scopus2-s2.0-79955020765en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.fertnstert.2011.01.030
dc.identifier.urihttps://hdl.handle.net/11616/95305
dc.identifier.volume95en_US
dc.identifier.wosWOS:000289620900067en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofFertility and Sterilityen_US
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBreast canceren_US
dc.subjectemergency fertility preservationen_US
dc.subjectembryo freezingen_US
dc.subjectletrozoleen_US
dc.titleRandom-start controlled ovarian hyperstimulation for emergency fertility preservation in letrozole cyclesen_US
dc.typeEditorialen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu