The Effects of Remifentanil on Hemodynamic Response Attenuation After Electroconvulsive Therapy Under Sevoflurane Anesthesia

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dc.authoridÇOLAK, CEMİL/0000-0001-5406-098X
dc.authoridDurmus, Mahmut/0000-0001-9594-9064
dc.authoridOZGUL, Ulku/0000-0003-3738-1751
dc.authoridErdil, Feray Akgül/0000-0002-7544-3717
dc.authoridErdogan Kayhan, Gulay/0000-0002-2635-9295
dc.authoridSanli, Mukadder/0000-0003-1009-5536
dc.authorwosidÇOLAK, CEMİL/ABI-3261-2020
dc.authorwosidDurmuş, Mahmut/AAG-3377-2019
dc.authorwosidDurmus, Mahmut/ABH-3006-2020
dc.authorwosidOZGUL, Ulku/ABI-6823-2020
dc.authorwosidErdil, Feray Akgül/ABI-2474-2020
dc.authorwosidErdogan Kayhan, Gulay/JVZ-0037-2024
dc.authorwosidSanli, Mukadder/ABI-8124-2020
dc.contributor.authorErdil, Feray
dc.contributor.authorOzgul, Ulku
dc.contributor.authorSanli, Mukadder
dc.contributor.authorKayhan, Gulay
dc.contributor.authorColak, Cemil
dc.contributor.authorDurmus, Mahmut
dc.date.accessioned2024-08-04T20:44:07Z
dc.date.available2024-08-04T20:44:07Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPurpose We evaluated the effects of a single loading dose of remifentanil (1 g/kg) administered as an adjunct to sevoflurane, on the duration of seizure activity, recovery times, and hemodynamic profiles, during electroconvulsive therapy. Methods The patients were randomly allocated to receive sevoflurane-saline (Group SS) or sevoflurane-remifentanil (Group SR). Sevoflurane (8%) was initiated for anesthesia induction in both groups until loss of consciousness was achieved. Remifentanil was then administered to Group SR via a 1-g/kg intravenous bolus. Patients in Group SS received saline in the same manner. Mean arterial pressure (MAP) and heart rate (HR) were recorded before anesthetic induction (T1), at the loss of consciousness (T2), and at 0, 1, 3, and 10 minutes after the electrical stimuli were completed (T3, T4, T5, and T6, respectively). Results Compared with the baseline values, HR increased significantly in Group SS at times T2 and T4 to T6 and decreased significantly in Group SR at time T2. When the groups were compared, we found that HR decreased significantly in Group SR at T2 and T4 to T6. Compared with baseline, MAP increased in Group SS between T3 and T6, and MAP decreased in Group SR at T2 and increased at T3 to T4. Mean arterial pressure decreased to a greater extent in Group SR than in Group SS during the T2 to T6 period. There were no group differences in seizure duration or recovery time. Conclusions The addition of 1-g/kg remifentanil to anesthetic induction with sevoflurane attenuated the acute hemodynamic response to electroconvulsive therapy under sevoflurane anesthesia without adversely affecting the duration of seizure activity or the recovery profile.en_US
dc.identifier.doi10.1097/YCT.0000000000000411
dc.identifier.endpage267en_US
dc.identifier.issn1095-0680
dc.identifier.issn1533-4112
dc.identifier.issue4en_US
dc.identifier.pmid28520577en_US
dc.identifier.scopus2-s2.0-85036517456en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage264en_US
dc.identifier.urihttps://doi.org/10.1097/YCT.0000000000000411
dc.identifier.urihttps://hdl.handle.net/11616/98048
dc.identifier.volume33en_US
dc.identifier.wosWOS:000416839600023en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal of Ecten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectelectroconvulsive therapyen_US
dc.subjectremifentanilen_US
dc.subjectmajor depressionen_US
dc.subjectsevofluraneen_US
dc.subjecthemodynamicen_US
dc.titleThe Effects of Remifentanil on Hemodynamic Response Attenuation After Electroconvulsive Therapy Under Sevoflurane Anesthesiaen_US
dc.typeArticleen_US

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