Enhanced role of multipair donor swaps in response to size incompatibility: The first two 5-way and the first 6-way liver paired exchanges

dc.authorscopusid7102264810
dc.authorscopusid6603418564
dc.authorscopusid8368305600
dc.authorscopusid36666519800
dc.authorscopusid25959851900
dc.authorscopusid55324267500
dc.authorscopusid8378959500
dc.contributor.authorYilmaz S.
dc.contributor.authorSönmez T.
dc.contributor.authorÜnver M.U.
dc.contributor.authorInce V.
dc.contributor.authorAkbulut S.
dc.contributor.authorSarici K.B.
dc.contributor.authorIsik B.
dc.date.accessioned2024-08-04T20:02:32Z
dc.date.available2024-08-04T20:02:32Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractA significant portion of liver transplantations in many countries is conducted via living-donor liver transplantation (LDLT). However, numerous potential donors are unable to donate to their intended recipients due to factors such as blood type incompatibility or size incompatibility. Despite this, an incompatible donor for one recipient may still be a viable donor for another patient. In recent decades, several transplant centers have introduced liver paired exchange (LPE) programs, facilitating donor exchanges between patients and their incompatible donors, thereby enabling compatible transplants. Initially, LPE programs in Asia primarily involved ABO-i pairs, resulting in 2-way exchanges mainly between blood type A and B recipients and donors. This practice has led to a modest 1% to 2% increase in LDLTs at some centers. Incorporating size incompatibility alongside blood type incompatibility further enhances the efficacy and significance of multiple-pair LPEs. Launched in July 2022, a single-center LPE program established at Inonu University Liver Transplant Institute in Malatya, Türkiye, has conducted thirteen 2-way, nine 3-way, four 4-way, two 5-way, and one 6-way LPEs until February 2024. In 2023 alone, this program facilitated 64 LDLTs, constituting 27.7% of the total 231 LDLTs performed. This paper presents the world's first two 5-way LPEs and the first 6-way LPE. © 2024 The Authorsen_US
dc.description.sponsorshipThe authors would also like to thank the Surgical and Anesthesia teams participating in the surgery.en_US
dc.identifier.doi10.1016/j.ajt.2024.05.013
dc.identifier.issn1600-6135
dc.identifier.pmid38768752en_US
dc.identifier.scopus2-s2.0-85195189150en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajt.2024.05.013
dc.identifier.urihttps://hdl.handle.net/11616/91750
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier B.V.en_US
dc.relation.ispartofAmerican Journal of Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectliver paired donationen_US
dc.subjectliver paired exchangeen_US
dc.subjectliving-donor liver transplantationen_US
dc.titleEnhanced role of multipair donor swaps in response to size incompatibility: The first two 5-way and the first 6-way liver paired exchangesen_US
dc.typeArticleen_US

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