The hematologic manifestations of pediatric celiac disease at the time ofdiagnosis and efficiency of gluten-free diet

dc.contributor.authorÇatal, Ferat
dc.contributor.authorTopal, Erdem
dc.contributor.authorErimiştekin, Halime
dc.contributor.authorYıldırım, Nurdan Acar
dc.contributor.authorSinanoğlu, Muhammed Selçuk
dc.contributor.authorKarbiber, Hamza
dc.contributor.authorSelimoğlu, Mukadder Ayşe
dc.date.accessioned2020-05-09T19:50:44Z
dc.date.available2020-05-09T19:50:44Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractÖz (İngilizce): Background/aim: To determine the hematologic manifestations at the time of diagnosis of celiac disease in children and the effects of a gluten-free diet on hematologic signs upon follow-up. Materials and methods: The records of patients with celiac disease who received a follow up examination at the Pediatric Gastroenterology Clinic between June 2006 and June 2013 were retrospectively examined. Results: Ninety-one patients were included in the study. The mean age at diagnosis was 8.1 ± 4.21 years and 59 patients (64.8%) were female. Thirty-two patients (35.2%) had hematologic signs at the time of diagnosis. Anemia (24.2%) was the most common hematologic sign, followed by thrombocytosis (16.5%) and leukopenia (4.4%). The tTG IgA titers were screened in 80 of the 91 patients during diagnosis. Follow-up examinations found that remission for anemia (P = 0.017), thrombocytosis (P = 0.039), and decreases in tTG IgA titers (P = 0.034) were more prominent in patients who had followed a strict gluten-free diet. Conclusion: Approximately one-third of the celiac disease patients had hematologic manifestations at the time of diagnosis. Remission in hematologic signs and decrease in tTG IgA titers were more prominent in patients who had adhered to a gluten-free diet.en_US
dc.identifier.citationFerat Ç., Erdem T., Halime E., Nurdan ACAR Y., Muhammed Selçuk S., Hamza KARBİBER , Mukadder Ayşe S. (2015). The hematologic manifestations of pediatric celiac disease at the time ofdiagnosis and efficiency of gluten-free diet, Turkish Journal of Medical Sciences, İnönü Üniversitesi, Malatya.en_US
dc.identifier.endpage667en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue3en_US
dc.identifier.startpage663en_US
dc.identifier.trdizinid172723en_US
dc.identifier.urihttps://hdl.handle.net/11616/15477
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/172723
dc.identifier.volume45en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.publisherTurkish Journal of Medical Sciencesen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCerrahien_US
dc.titleThe hematologic manifestations of pediatric celiac disease at the time ofdiagnosis and efficiency of gluten-free dieten_US
dc.typeArticleen_US

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