An Adolescent Girl with the Recurrent Attacks of Different Type of Thromboses

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dc.authoridsozeri, betul/0000-0002-5079-5644
dc.authoridZirhli Selcuk, Senay/0000-0002-7886-2984
dc.authoridTabel, Yilmaz/0000-0001-7359-4944
dc.authorwosidsozeri, betul/A-3151-2019
dc.contributor.authorSelcuk, Senay Zirhli
dc.contributor.authorÖncül, Yurday
dc.contributor.authorDurmus, Hanim
dc.contributor.authorSozeri, Betul
dc.contributor.authorTabel, Yilmaz
dc.date.accessioned2024-08-04T20:53:41Z
dc.date.available2024-08-04T20:53:41Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Thrombosis is less common in childhood compared to adults and is usually acquired. Here, we present a patient who had recurrent thrombosis in different organs and was diagnosed with lupus secondary antiphospholipid syndrome (APS) when the lupus anticoagulant test was positive in the follow-up, which we treated quickly and effectively considering possible catastrophic prognosis due to kidney involvement in the same week. Case Report: Fifteen-year-old girl who presented to the emergency department with complaints of sensitivity, pain, and swelling in her left leg. Her medical history revealed recurrent thrombosis attacks and development of mental retardation after a seizure at around the age of three, and no underlying disease had been identified to date. Her family history revealed that her aunt had complained of hand swelling after cold exposure. No significant finding was detected in her thrombophilia panel. A thrombophilia panel was conducted, but no significant findings were detected. Due to a positive lupus anticoagulant test, the patient was diagnosed with APS. The diagnosis of systemic lupus erythematosus was also considered secondary to APS after positive results for anti-nuclear antibody (ANA) and dsDNA tests. Due to the recurrent thrombosis attacks and kidney involvement, a possible catastrophic outcome was considered. In addition to the on going heparin, warfarin, and aspirin therapy, high-dose steroids, cyclophosphamide, intravenous immunoglobulin, and 5 sessions of plasmapheresis were administered, and all treatments were met with a positive response. Conclusion: In this case presentation, we wanted to emphasize that despite the difficulties in the differential diagnosis of thrombosis in children and especially the diagnosis of catastrophic antiphospholipid syndrome (CAPS), prompt and effective treatment can be life-saving.en_US
dc.identifier.doi10.4274/jcp.2023.29053
dc.identifier.endpage106en_US
dc.identifier.issn1304-9054
dc.identifier.issn1308-6308
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85158138645en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage102en_US
dc.identifier.urihttps://doi.org/10.4274/jcp.2023.29053
dc.identifier.urihttps://hdl.handle.net/11616/101339
dc.identifier.volume21en_US
dc.identifier.wosWOS:001061419800014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofGuncel Pediatri-Journal of Current Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntiphospholipid antibodiesen_US
dc.subjectantiphospholipid syndromeen_US
dc.subjectcatastrophic antiphospholipid syndromeen_US
dc.subjectchilden_US
dc.subjectthrombosisen_US
dc.titleAn Adolescent Girl with the Recurrent Attacks of Different Type of Thrombosesen_US
dc.typeArticleen_US

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