Synthesis, antioxidant and anti-microbial properties of two organoselenium compounds

dc.authoridYılmaz, İsmet/0000-0002-7204-1050
dc.authoridGünal, Selami/0000-0002-4752-5176
dc.authoridAteş, Burhan/0000-0001-6080-229X
dc.authorwosidYılmaz, İsmet/P-9976-2015
dc.authorwosidGök, Yetkin/AAA-5669-2021
dc.authorwosidGünal, Selami/AAA-7246-2021
dc.authorwosidÖzdemir, İlknur/AAA-6216-2021
dc.authorwosidYılmaz, ismet/AAG-8946-2019
dc.authorwosidAteş, Burhan/AAA-3730-2021
dc.contributor.authorTalas, Zeliha Selamoglu
dc.contributor.authorGok, Yetkin
dc.contributor.authorOzdemir, Ilknur
dc.contributor.authorAtes, Burhan
dc.contributor.authorGunal, Selami
dc.contributor.authorYilmaz, Ismet
dc.date.accessioned2024-08-04T20:40:08Z
dc.date.available2024-08-04T20:40:08Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim of this study is synthesis of two different series of organoselenium compounds and available in vitro antioxidant and antimicrobial properties of thee synthetic compounds. The synthetic compounds were identified by H-1-NMR (300 MHz), C-13-NMR (75.5 MHz), FT-IR spectroscopic techniques and micro analysis. Antioxidant properties of two synthetic organoselenium compounds were determined by 1,1- dipheny1-2-picrylhydrazyl (DPPH) radical method, reducing power assay and beta-carotene bleaching method as in vitro. Antimicrobial effects of samples were assessed by the agar dilution procedure and using gram positive and gram-negative bacteria and yeast strains. Although 1,3-di-pmethoxybenzylpyrimidine-2-selenone showed better antiradical activity in DPPH test and higher protective activity on beta-carotene, 1-isopropyl-3-methylbenzimidazole-2-selenone was found to be better in reducing power and antimicrobial activity.en_US
dc.description.sponsorshipTechnological and Scientific Research Council of Turkey TUBITAK [TBAG-2259 (102T185)]en_US
dc.description.sponsorshipWe thank to Technological and Scientific Research Council of Turkey TUBITAK TBAG-2259 (102T185) for financial support of this work.en_US
dc.identifier.endpage616en_US
dc.identifier.issn1011-601X
dc.identifier.issue2en_US
dc.identifier.pmid25730792en_US
dc.identifier.scopus2-s2.0-84924956440en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage611en_US
dc.identifier.urihttps://hdl.handle.net/11616/96713
dc.identifier.volume28en_US
dc.identifier.wosWOS:000351657400030en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherUniv Karachien_US
dc.relation.ispartofPakistan Journal of Pharmaceutical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSynthetic organoselenium compoundsen_US
dc.subjectantioxidant activityen_US
dc.subjectantimicrobial activityen_US
dc.titleSynthesis, antioxidant and anti-microbial properties of two organoselenium compoundsen_US
dc.typeArticleen_US

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