Effects of contrast material on the metabolite ratios in single-voxel MR Spectroscopy of intraaxial brain tumors

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dc.authoridERBAY, MEHMET FATİH/0000-0002-1596-3147
dc.authoridaralasmak, ayse/0000-0001-8654-855X
dc.authorwosidERBAY, MEHMET FATİH/ABI-2942-2020
dc.authorwosidBurulday, Veysel/V-6075-2017
dc.authorwosidaralasmak, ayse/Y-5820-2018
dc.contributor.authorAlkan, Alpay
dc.contributor.authorBurulday, Veysel
dc.contributor.authorOztanir, Namik
dc.contributor.authorDogan, Metin
dc.contributor.authorErbay, Mehmet Fatih
dc.contributor.authorKocak, Ayhan
dc.contributor.authorAralasmak, Ayse
dc.date.accessioned2024-08-04T20:36:00Z
dc.date.available2024-08-04T20:36:00Z
dc.date.issued2012
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: The purpose of our study was to determine whether the administration of contrast material affects the results of MR Spectroscopy (MRS) in different intraaxial brain tumors. Materials and methods: Thirty-three patients (median range 46.72 +/- 2.95, range 9-77) with intraaxial brain tumors underwent MRS before and 5 min after intravenous administration of gadolinium based contrast material at the standard dose of 0.1 mmol/kg (Gadodiamide or Gd-DOTA). Metabolite ratios (N-acetyl aspartate (NAA)/Creatine (Cr), Choline (Cho)/Cr. and NAA/Cho) were calculated. Results: There was no significant difference between the pre and postcontrast MRS spectra as regards to NAA/Cr (p:0.4), Cho/Cr (p:0.2), and NAA/Cho (p:0.2) ratios obtained from the intraaxial brain tumors. Conclusion: Contrast material administration did not change the metabolite ratios of MRS. Contrast administration would be useful in guiding voxel localization in MRS evaluation of intraaxial brain tumors. (C) 2012 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.mehy.2012.03.029
dc.identifier.endpage131en_US
dc.identifier.issn0306-9877
dc.identifier.issue2en_US
dc.identifier.pmid22560442en_US
dc.identifier.scopus2-s2.0-84863333032en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage129en_US
dc.identifier.urihttps://doi.org/10.1016/j.mehy.2012.03.029
dc.identifier.urihttps://hdl.handle.net/11616/95710
dc.identifier.volume79en_US
dc.identifier.wosWOS:000306770700002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherChurchill Livingstoneen_US
dc.relation.ispartofMedical Hypothesesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntracranial Mass Lesionsen_US
dc.subjectGd-Contrasten_US
dc.subjectIn-Vitroen_US
dc.titleEffects of contrast material on the metabolite ratios in single-voxel MR Spectroscopy of intraaxial brain tumorsen_US
dc.typeArticleen_US

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