The investigation of effects of proton pump inhibitors

dc.contributor.authorAsutay, Fatih
dc.contributor.authorAtalay, Yusuf
dc.contributor.authorAcar, Ahmet Huseyin
dc.date.accessioned2022-02-22T14:31:47Z
dc.date.available2022-02-22T14:31:47Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAim: Proton pump inhibitors (PPI) have been widely used throughout the world. The effects of the PPIs on bone mineral density (BMD) is important for oral surgeons. The aim of this study was evaluate alterations in bone mineral density in patients using PPI. Material and Methods: A total of 92 patients were enrolled in the study and were separated into 4 groups (24 in control group, 22 in Lansoprazole group, 24 in Pantoprazole group and 22 in Esomeprazole group). Hounsfield Unit scores were measuredseparately of the incisor, canine, premolar, molar and tubule regions in the jaws with computed tomography. The measurement area in the dental regions was defined as an area of 2mm2 at least 2mm from the apex of the teeth. All data were collected and statistically analysed. Results: There was no significant difference between the groups in respect of mean age. There were no significant differences between the control and the study groups. Also no significant difference was found among the study groups. Conclusion: These data revealed that there were no correlations between decreased maxillary bone mineral density and proton pump inhibitor use. Further studies with more extensive samples should take into consideration drug doses and the period of use.en_US
dc.identifier.citationAsutay, F., Atalay, Y., & Huseyin Acar, A. (2021). The investigation of effects of proton pump inhibitors . Annals of Medical Researchen_US
dc.identifier.urihttps://hdl.handle.net/11616/53862
dc.language.isoenen_US
dc.relation.ispartofAnnals of Medical Researchen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe investigation of effects of proton pump inhibitorsen_US
dc.typeArticleen_US

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