Vestibüler uyarılmış miyojenik potansiyellerde farklı protokollerin meniere hastalığında teşhis değeri
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Tarih
2024
Yazarlar
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Cilt Başlığı
Yayıncı
İnönü Üniversitesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmanın amacı Vestibüler Uyarılmış Miyojenik Potansiyellerde farklı kayıt protokollerinin Meniere Hastalığı tanısındaki katkısını değerlendirmektir. Materyal ve Metot: Araştırma Malatya İnönü Üniversitesi Turgut Özal Tıp Merkezi Odyoloji kliniğinde, daha önce Kesin Meniere Hastalığı teşhisi almış 18-55 yaş arası bireyler ve kontrol grubu için benzer yaş aralığındaki sağlıklı gönüllü bireyler ile gerçekleştirilmiştir. Araştırmanın vaka grubuna dahil edilme kriterlerini sağlayan Kesin Meniere Hastalığı tanısı almış 26 birey ve kontrol grubuna 24 sağlıklı birey dahil edilmiştir. Çalışmaya katılan bireylere 500, 750 ve 1000 Hz frekanslarında hava yolu ve kemik yolu tone burst uyaran kullanılarak Servikal Vestibüler Uyarılmış Miyojenik Potansiyeller (s-VEMP) Testive Oküler Vestibüler Uyarılmış Miyojenik Potansiyeller (o-VEMP) Testi uygulanmıştır. Bulgular: Çalışmaya katılan vaka grubundaki bireylerin hava yolu ve kemik yolu s-VEMP testinde dalga görülme oranı, P1-N1 amplitüd, amplitüd asimetri ve frekanslar arası amplitüd oranı değerlerinde etkilenen kulak, etkilenmeyen kulak ve kontrol grubu arasında istatistiksel açıdan anlamlı farklılık bulunmuştur (p<0.05). O-VEMP testinde ise N1 latans, P1 latans, N1-P1 amplitüd, amplitüd asimetri ve frekanslar arası amplitüd oranı değerlerinde etkilenen kulak, etkilenmeyen kulak ve kontrol grubu arasında istatistiksel açıdan anlamlı farklılık bulunmuştur (p<0.05). Sonuç: Meniere hastalarında endolenfatik hidrops sonucu otolit organların rezonans frekansının yükselmesi nedeniyle VEMP testinde maksimum amplitüd frekansı sağlıklı bireylere göre daha yüksek frekanslara kayar. Bu nedenle frekanslar arası amplitüd oranı Meniere Hastalığı teşhisini kolaylaştıran bir parametre olarak kullanılabilir.
Aim: The aim of this study is to evaluate the contribution of different recording protocols in Vestibular Evoked Myogenic Potentials in the diagnosis of Meniere's Disease. Materials and Methods: The research was conducted at Malatya İnönü University Turgut Özal Medical Center Audiology Clinic, between October 2023 and November 2023, for individuals between the ages of 18-55 who were previously diagnosed with Meniere's Disease at the Ear Nose and Throat Diseases Polyclinic, and for the control group, healthy individuals in the same age range. It was carried out with volunteers. 26 individuals with a definite diagnosis of Meniere's Disease who met the inclusion criteria in the case group of the study and 24 healthy individuals in the control group were included. Cervical Vestibular Evoked Myogenic Potentials Test and Ocular Vestibular Evoked Myogenic Potentials Test were applied to the individuals participating in the study using air conduction and bone conduction tone burst stimulation at frequencies of 500, 750 and 1000 Hz. Results: In the air conduction and bone conduction c-VEMP test of the individuals in the case group participating in the study, a statistically significant difference was found in the wave incidence rate, P1-N1 amplitude, amplitude asymmetry and inter-frequency amplitude ratio values between the affected ear, unaffected ear and the control group (p< 0.05). In the O-VEMP test, a statistically significant difference was found between the affected ear, unaffected ear and the control group in the values of N1 latency, P1 latency, N1-P1 amplitude, amplitude asymmetry and inter-frequency amplitude ratio (p<0.05). Conclusion: Due to the increase in the resonance frequency of otolith organs in Meniere's patients as a result of endolymphatic hydrops, the maximum amplitude frequency in the VEMP test shifts to higher frequencies compared to healthy individuals, and the amplitude ratio between frequencies can be used as a parameter that facilitates the diagnosis of Meniere's Disease.
Aim: The aim of this study is to evaluate the contribution of different recording protocols in Vestibular Evoked Myogenic Potentials in the diagnosis of Meniere's Disease. Materials and Methods: The research was conducted at Malatya İnönü University Turgut Özal Medical Center Audiology Clinic, between October 2023 and November 2023, for individuals between the ages of 18-55 who were previously diagnosed with Meniere's Disease at the Ear Nose and Throat Diseases Polyclinic, and for the control group, healthy individuals in the same age range. It was carried out with volunteers. 26 individuals with a definite diagnosis of Meniere's Disease who met the inclusion criteria in the case group of the study and 24 healthy individuals in the control group were included. Cervical Vestibular Evoked Myogenic Potentials Test and Ocular Vestibular Evoked Myogenic Potentials Test were applied to the individuals participating in the study using air conduction and bone conduction tone burst stimulation at frequencies of 500, 750 and 1000 Hz. Results: In the air conduction and bone conduction c-VEMP test of the individuals in the case group participating in the study, a statistically significant difference was found in the wave incidence rate, P1-N1 amplitude, amplitude asymmetry and inter-frequency amplitude ratio values between the affected ear, unaffected ear and the control group (p< 0.05). In the O-VEMP test, a statistically significant difference was found between the affected ear, unaffected ear and the control group in the values of N1 latency, P1 latency, N1-P1 amplitude, amplitude asymmetry and inter-frequency amplitude ratio (p<0.05). Conclusion: Due to the increase in the resonance frequency of otolith organs in Meniere's patients as a result of endolymphatic hydrops, the maximum amplitude frequency in the VEMP test shifts to higher frequencies compared to healthy individuals, and the amplitude ratio between frequencies can be used as a parameter that facilitates the diagnosis of Meniere's Disease.
Açıklama
Anahtar Kelimeler
Kulak Burun ve Boğaz, Otorhinolaryngology (Ear-Nose-Throat)
