Assessment of left atrial volume and function by real time three-dimensional echocardiography in obese patients

dc.authoridCansel, Mehmet/0000-0003-4740-4371
dc.authoridHidayet, Şıho/0000-0002-4103-9345
dc.authoridÖzyalın, Fatma/0000-0001-6486-6389
dc.authoridözyalın, fatma/0000-0001-6486-6389
dc.authoridAkaycan, Jülide/0000-0002-9174-6777
dc.authorwosidCansel, Mehmet/ABI-6324-2020
dc.authorwosidErmis, Necip/A-5184-2018
dc.authorwosidErmis, Necip/HJP-7061-2023
dc.authorwosidHidayet, Şıho/ABI-2256-2020
dc.authorwosidÖzyalın, Fatma/ABC-7193-2020
dc.authorwosidözyalın, fatma/ABA-5258-2020
dc.authorwosidAkaycan, Jülide/ABI-2397-2020
dc.contributor.authorYagmur, Julide
dc.contributor.authorCansel, Mehmet
dc.contributor.authorKurtoglu, Ertugrul
dc.contributor.authorHidayet, Siho
dc.contributor.authorAcikgoz, Nusret
dc.contributor.authorErmis, Necip
dc.contributor.authorOzyalin, Fatma
dc.date.accessioned2024-08-04T20:42:52Z
dc.date.available2024-08-04T20:42:52Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To evaluate left atrial (LA) volume and functions in obese subjects using real time three-dimensional echocardiography (RT3DE) and also the relationship between LA mechanical functions and N-terminal pro-atrial natriuretic peptide (NT-proANP). Methods: This study included 40 obese (26 females and 14 males, mean age 51.9 years) and 40 normal weight subjects (23 females and 16 males, mean age 53.5 years) with normal coronary angiograms. All the study participants underwent RT3DE to assess LA volume and mechanical function. Plasma NT-proANP was determined by ELISA method. Results: There was no significant difference between groups in left ventricular (LV) diameters and ejection fraction, which reflect LV systolic function. However, transmitral deceleration time, isovolumetric relaxation time, and peak late diastolic tissue Doppler velocity values, which reflect LV diastolic function, were found to be significantly higher in obese subjects when compared with controls. LA maximum volume (LAVmax), LAVmax index (LAVI), LA minimal volume (LAVmin), before atrial contraction volume (LAVpreA), LA active emptying volume, LA total emptying volume, and LA active emptying fraction, which reflect LA reservoir and pump functions, were also higher in obese subjects when compared with controls. LA passive emptying fraction was significantly lower in obese subjects than in controls. NT-proANP levels were similar between groups. There were positive correlations between NT-proANP level and LAVI, LAVmax, LAVmin, LAVpreA, and LA total and active emptying volumes. Conclusions: Left atrial mechanical functions and volumes are impaired in obese subjects. These findings may be regarded as early markers of subclinical cardiac failure in obese subjects who have not yet exhibited any clinical evidence of cardiovascular disease.en_US
dc.identifier.doi10.1111/echo.13417
dc.identifier.endpage216en_US
dc.identifier.issn0742-2822
dc.identifier.issn1540-8175
dc.identifier.issue2en_US
dc.identifier.pmid27933639en_US
dc.identifier.scopus2-s2.0-85006836482en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage210en_US
dc.identifier.urihttps://doi.org/10.1111/echo.13417
dc.identifier.urihttps://hdl.handle.net/11616/97640
dc.identifier.volume34en_US
dc.identifier.wosWOS:000397407700008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofEchocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniquesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectechocardiographyen_US
dc.subjectleft atrial volumeen_US
dc.subjectobesityen_US
dc.titleAssessment of left atrial volume and function by real time three-dimensional echocardiography in obese patientsen_US
dc.typeArticleen_US

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