Is Prognostic Nutritional Index an Indicator for Postoperative 90-Day Mortality in Laparoscopic Gastric Cancer Surgery?

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dc.authoridAydın, Mehmet Can/0000-0002-2379-1293
dc.authoridBag, Yusuf Murat/0000-0002-0159-9356
dc.authoridSumer, Fatih/0000-0002-0557-1369
dc.authoridZengin, Akile/0000-0003-0981-8901
dc.authorwosidKocaaslan, Hüseyin/HHZ-0946-2022
dc.authorwosidAydın, Mehmet Can/ABC-6499-2021
dc.authorwosidBag, Yusuf Murat/ABD-2949-2021
dc.authorwosidSumer, Fatih/F-8042-2017
dc.authorwosidZengin, Akile/AAX-7682-2020
dc.contributor.authorZengin, Akile
dc.contributor.authorBag, Yusuf Murat
dc.contributor.authorAydin, Mehmet Can
dc.contributor.authorKocaaslan, Huseyin
dc.contributor.authorKaplan, Kuntay
dc.contributor.authorSumer, Fatih
dc.contributor.authorKayaalp, Cuneyt
dc.date.accessioned2024-08-04T20:50:52Z
dc.date.available2024-08-04T20:50:52Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractGastic cancer is a life-threatening malignancy in the world. The aim of this study was to investigate the clinical significance of the prognostic nutritional index (PNI) as a guiding marker for gastric cancer patients with laparoscopic gastrectomy. We retrospectively examined the medical records of 138 gastric cancer patients who had adenocarcinoma pathological diagnosis and operated laparoscopically. Patients were divided into two groups (survived and death) and these groups were compared with clinical and laboratory parameters results. The PNI was calculated as 10 x serum albumin (g/dL) + 0.005 x total lymphocyte count (per mm(3)). Logistic regression analyses were performed to identify the risk factors of 90-day mortality. The median age of the study cohort was 62.5 (19-91) years, 98 (71%) were males, and 9 (6.5%) patients died during the 90-day after laparoscopic gastrectomy. The PNI levels were significantly lower in death group compared with survived group 37.5 (25-47.1) to 46.9 (22.8-64.9). The PNI (Odds Ratio = 0.81, 95% Confidence Interval 0.70-0.92, p = 0.003) was found as an independent factor for 90-day mortality in multivariate analysis. Receiver operating characteristic (ROC) curve analysis showed that 45.15 is the best-cutoff value for 90-day mortality after laparoscopic gastrectomy. 90-day mortality rate of PNI > 45.15 was 2.2% and PNI <= 45.15 was 13.6% found. Lower PNI is associated with increased 90-day mortality in laparoscopic gastrectomy for gastric cancer. The PNI may be a useful marker for predicting the 90-day mortality of gastric cancer patients after laparoscopic gastrectomy.en_US
dc.identifier.doi10.1080/01635581.2021.2002920
dc.identifier.endpage2094en_US
dc.identifier.issn0163-5581
dc.identifier.issn1532-7914
dc.identifier.issue6en_US
dc.identifier.pmid34779330en_US
dc.identifier.scopus2-s2.0-85119440816en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2088en_US
dc.identifier.urihttps://doi.org/10.1080/01635581.2021.2002920
dc.identifier.urihttps://hdl.handle.net/11616/100318
dc.identifier.volume74en_US
dc.identifier.wosWOS:000718740300001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherRoutledge Journals, Taylor & Francis Ltden_US
dc.relation.ispartofNutrition and Cancer-An International Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGastrectomyen_US
dc.subjectSurvivalen_US
dc.subjectAggressivenessen_US
dc.subjectConversionen_US
dc.subjectPredictsen_US
dc.subjectOutcomesen_US
dc.titleIs Prognostic Nutritional Index an Indicator for Postoperative 90-Day Mortality in Laparoscopic Gastric Cancer Surgery?en_US
dc.typeArticleen_US

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