Anaesthesia induction with ketamine:Propofol combination (ketofol) in caesarean delivery

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dc.authorscopusid22956895300
dc.authorscopusid55666804700
dc.authorscopusid55898386700
dc.authorscopusid55894080100
dc.authorscopusid55898201200
dc.authorscopusid34569135700
dc.authorscopusid7004486274
dc.contributor.authorKayhan G.E.
dc.contributor.authorToprak H.I.
dc.contributor.authorAslan A.
dc.contributor.authorÇolak Y.Z.
dc.contributor.authorGülhaş N.
dc.contributor.authorDurmuş M.
dc.contributor.authorErsoy M.Ö.
dc.date.accessioned2024-08-04T20:02:06Z
dc.date.available2024-08-04T20:02:06Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to compare the maternal and foetal effects of ketamine:propofol (ketofol) combination with thiopental, used in anaesthesia induction for caesarean delivery. Methods: Eighty, 18-35 years-old parturients in ASA I-II class, who were admitted for caesarean delivery under general anaesthesia, were allocated to this prospective, double-blind, randomised study. Patients were divided into two groups according to thiopental (Group T) or ketofol (Group K) administration. In anaesthesia induction, 4 mg kg-1 thiopental for Group T, 1 mg kg-1 ketamin + 1 mg kg-1 propofol (ketofol) for Group K were administered. Haemodynamic effects, BIS values, foetal parameters in the perioperative period and postoperative pain levels and morphine consumption were evaluated. Results: There were no significant differences between groups with regard to demographic data. Heart rate values were lower in Group K than Group T and there were significant differences between values immediately after intubation and 15 min after intubation. There were no significant differences in systolic and diastolic blood pressures between the two groups. Apgar scores recorded at the 5th minute were higher in Group K, while there were no differences in the 1st minute scores between groups (p=0.01). Upon analyses of umbilical artery blood gas, pH values were higher in Group K (p=0.034). While pain scores were similar in groups, total morphine consumption for 24 hours was found to be higher in Group K (p=0.008). Conclusion: We believe that 1 mg kg-1 ketofol (1:1), when used for anaesthesia induction of caesarean delivery, may be a good alternative to thiopental in terms of maternal and especially foetal effects; however, patients need to be followed closely for postoperative analgesic requirements. © 2013 by Turkish Anaesthesiology and Intensive Care Society.en_US
dc.identifier.doi10.5152/TJAR.2013.28
dc.identifier.endpage136en_US
dc.identifier.issn1304-0871
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-84886292287en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage131en_US
dc.identifier.urihttps://doi.org/10.5152/TJAR.2013.28
dc.identifier.urihttps://hdl.handle.net/11616/91428
dc.identifier.volume41en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyon Dernegi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCaesarean sectionen_US
dc.subjectGeneral anesthesiaen_US
dc.subjectKetofolen_US
dc.subjectThiopentalen_US
dc.titleAnaesthesia induction with ketamine:Propofol combination (ketofol) in caesarean deliveryen_US
dc.title.alternativeSezaryende ketamin:Propofol kombinasyonu (ketofol) ile anestezi i?ndüksiyonuen_US
dc.typeArticleen_US

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