The effects of dexmedetomidine and fentanyl on emergence characteristics after adenoidectomy in children

Basit Öğe Kaydı
dc.authoridErsoy, Mehmet/0000-0002-0724-2825
dc.authoridbegeç, zekine/0000-0002-9506-1871
dc.authoridErdil, Feray Akgül/0000-0002-7544-3717
dc.authoridUlger, Hacer/0000-0002-8579-0528
dc.authorwosidErsoy, Mehmet/ACN-2779-2022
dc.authorwosidUlger, Hacer/AAI-8829-2021
dc.authorwosidbegeç, zekine/ABI-5491-2020
dc.authorwosidErdil, Feray Akgül/ABI-2474-2020
dc.contributor.authorErdil, F.
dc.contributor.authorDemirbilek, S.
dc.contributor.authorBegec, Z.
dc.contributor.authorOzturk, E.
dc.contributor.authorUlger, M. H.
dc.contributor.authorErsoy, M. O.
dc.date.accessioned2024-08-04T20:31:15Z
dc.date.available2024-08-04T20:31:15Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis randomised controlled study evaluated the effects of fentanyl and dexmedetomidine on emergence characteristics of children having adenoidectomy and anaesthetised with sevoflurane. Ninety children, two to seven years of age and ASA physical status I, were studied. Children were randomly assigned to one of three groups of 30 children, with the study intervention injection given intravenously after intubation. Children in Group F received fentanyl 2.5 mu g.kg(-1), children in Group D received dexmedetomidine 0.5 mu g.kg(-1) and children in Group C received saline solution. Anaesthesia was induced with 50% N(2)O and 8% sevoflurane in O(2) by mask and atracurium 0.6 mg.kg(-1) was administered for tracheal intubation. All children received paracetamol 40 mg/kg rectally one hour preoperatively and dexamethasone 0.5 mg.kg(-1) intravenously. The time to extubation was shorter in Group D than Group E The eye-opening time was longer in Group F (161 +/- 5.3 minutes) than in Groups C (12.0 +/- 4.2 minutes) and D (12.7 +/- 3.2 minutes). The proportion of pain-free children in early recovery was significantly higher in Groups D (47%) and F (43%) than Group C (13%) (P < 0.05). The proportion of children with agitation scores > 3 was lower in Groups D 17% (5/30) and F 13% (4/30) than in Group C 47% (14/30) (P < 0.05). Fentanyl 2.5 mu g.kg(-1) and dexmedetomidine 0.5 mu g.kg(-1) had similar haemodynamic effects and emergence characteristics. Fentanyl has been safely used in children for many years. Further studies of dexmedetomidine safety and its interaction with other anaesthetic agents are required before recommending its routine use during general anaesthesia in children.en_US
dc.identifier.doi10.1177/0310057X0903700405
dc.identifier.endpage576en_US
dc.identifier.issn0310-057X
dc.identifier.issue4en_US
dc.identifier.pmid19681413en_US
dc.identifier.scopus2-s2.0-67649662245en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage571en_US
dc.identifier.urihttps://doi.org/10.1177/0310057X0903700405
dc.identifier.urihttps://hdl.handle.net/11616/94829
dc.identifier.volume37en_US
dc.identifier.wosWOS:000268850400009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAustralian Soc Anaesthetistsen_US
dc.relation.ispartofAnaesthesia and Intensive Careen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectemergence characteristicsen_US
dc.subjectsevofluraneen_US
dc.subjectdexmedetomidineen_US
dc.subjectfentanylen_US
dc.titleThe effects of dexmedetomidine and fentanyl on emergence characteristics after adenoidectomy in childrenen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu