Malon dialdehyde, nitrite and adrenomedullin levels in patients with premenstrual syndrome

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dc.authorscopusid7004200793
dc.authorscopusid22955309600
dc.authorscopusid7004547426
dc.authorscopusid6602510972
dc.authorscopusid6603965905
dc.authorscopusid6602072091
dc.contributor.authorBalat O.
dc.contributor.authorDikensoy E.
dc.contributor.authorUgur M.G.
dc.contributor.authorAtmaca R.
dc.contributor.authorCekmen M.
dc.contributor.authorYurekli M.
dc.date.accessioned2024-08-04T19:59:34Z
dc.date.available2024-08-04T19:59:34Z
dc.date.issued2007
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To assess the levels of malon dialdehyde (MDA); a lipid peroxide product, total nitrite; a stabile product of nitric oxide (NO), and adrenomedulin (AM), to determine whether their levels are altered in premenstrual syndrome (PMS) and to search for their possible pathophysiological role in this peculiar syndrome. Study design: Twenty-one patients aged between 28 and 37 years, who had regular menses for at least six previous cycles, and were in general good health condition, were taken into the study. Blood samples were obtained from each patient at the 3rd and 21st day of their menstrual cycles. AM, nitrite, MDA and estradiol levels have been assessed in these samples for each patient. Results: No statistically significant difference in terms of age, parity and body mass index was detected among groups (P > 0.05). Nitric oxide levels were higher on the 3rd day, compared to 21st day in the study group, and this difference was statistically significant (P < 0.05). In the study group, 21st day AM levels were significantly higher when compared to the control group (P < 0.05). Conclusion: Even though various stress symptoms are present in PMS, there is no change in the levels of MDA, an oxidative distress indicator but AM and NO may have a pathophysiological role on this enigmatic disease. © 2006 Springer-Verlag.en_US
dc.identifier.doi10.1007/s00404-006-0269-1
dc.identifier.endpage365en_US
dc.identifier.issn0932-0067
dc.identifier.issue5en_US
dc.identifier.pmid17063355en_US
dc.identifier.scopus2-s2.0-33947530840en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage361en_US
dc.identifier.urihttps://doi.org/10.1007/s00404-006-0269-1
dc.identifier.urihttps://hdl.handle.net/11616/90729
dc.identifier.volume275en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofArchives of Gynecology and Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdrenomedullinen_US
dc.subjectMalon dialdehydeen_US
dc.subjectNitric oxideen_US
dc.subjectPremenstrual syndromeen_US
dc.titleMalon dialdehyde, nitrite and adrenomedullin levels in patients with premenstrual syndromeen_US
dc.typeArticleen_US

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