Levels of Plasma C-reactive protein, Albumin and Pre-Albumin in Nigerian COVID-19 Patients
| dc.contributor.author | Arinola, Ganiyu Olatunbosun | |
| dc.contributor.author | Edem, Fabian Victory | |
| dc.contributor.author | Alonge, Temitope Oluwagbenga | |
| dc.date.accessioned | 2022-03-21T14:06:08Z | |
| dc.date.available | 2022-03-21T14:06:08Z | |
| dc.date.issued | 2022 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Aim: COVID-19 is a new viral, rapidly infectious and inflammatory disease, with no treatment currently.However, no study reported combination of high sensitive C-reactive protein (a marker of inflammation), albumin and prealbumin (markers of nutritional status) in the prognosis of COVID-19 among Nigerian COVID-19 patients. We assessed plasma levels of hsCRP, albumin, prealbumin, hsCRP albumin ratio and hsCRP-prealbumin ratio in newly admitted COVID-19 patients and COVID-19 patients at discharge. Material and Methods: Albumin, pre-albumin and C-RP levels were determined in the plasma of confirmed cases of COVID-19 recruited form one Infectious Diseases Center, Ibadan, Nigeria using ELISA. hsCRP-albumin ratio and hsCRP-prealbumin ratio were calculated. All these parameters were compared in both groups of patients and controls. Results: hsC-RP level was significantly higher in newly admitted COVID-19 patients compared with discharged COVID-19 patients or COVID-19 free control (p<0.05). There were no significant differences in plasma levels of albumin, prealbumin, hsCRP-albumin ratio and hsCRP-prealbumin ratio in both groups of COVID-19 patients compared with control (p>0.05).The mean values of plasma hsC-RP, albumin and prealbumin in most COVID-19 patients (89%, 100% and 91% respectively) were within normal reference ranges. hsC-RP were significantly increased in newly admitted COVID-19 patients who were females, above 40 years of age and stayed above 10 days of hospital admission (p<0.05 in each case). Conclusion: PlasmahsC-RP levelmight be a useful prognostic marker of COVID-19. Also COVID-19 in this group of patients exhibited low grade inflammation. | en_US |
| dc.identifier.citation | Arinola, G. O., Edem, F. V., & Alonge, T. O. (2022). Levels of Plasma C-reactive protein, Albumin and Pre-Albumin in Nigerian COVID-19 Patients. Annals of Medical Research | en_US |
| dc.identifier.uri | https://hdl.handle.net/11616/56717 | |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Annals of Medical Research | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Levels of Plasma C-reactive protein, Albumin and Pre-Albumin in Nigerian COVID-19 Patients | en_US |
| dc.type | Article | en_US |
