Cytotoxic effects of orthodontic composites

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dc.authoridSENGUN, Abdulkadir/0000-0002-6053-160X
dc.authoridULKER, Hayriye Esra/0000-0002-2967-5680
dc.contributor.authorMalkoc, Siddik
dc.contributor.authorCorekci, Bayram
dc.contributor.authorUlker, Hayriye Esra
dc.contributor.authorYalcin, Muhammet
dc.contributor.authorSengun, Abdulkadir
dc.date.accessioned2024-08-04T20:32:24Z
dc.date.available2024-08-04T20:32:24Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: To evaluate the cytotoxic effects of five different light-cured orthodontic bonding composites. Materials and Methods: The orthodontic composites Heliosit Orthodontic (Ivoclar), Transbond XT (3M Unitek), Bisco ORTHO (Bisco), Light Bond (Reliance), and Quick Cure (Reliance) were prepared, and the samples were extracted in 3 mL of BME (Basal Medium Eagle) with 10% newborn calf serum for 24 hours. The L929 cells were plated (25,000 cells/mL) in a 96-well dish and maintained in a humidified incubator for 24 hours at 37 degrees C, 5% CO(2), and 95% air. After 24 hours of incubation of the cells, the incubation medium was replaced by the immersed medium in which the samples were stored. Then, L929 cells were incubated in contact with eluates for 24 hours. The cell mitochondrial activity was evaluated by the methyl tetrazolium (MTT) test. Twelve wells were used for each specimen, and the MTT tests were applied two times. The data were statistically analyzed by one-way analysis of variance (ANOVA) and Tukey HSD tests. Results: Results with L929 fibroblasts demonstrated that except for Transbond XT, freshly prepared composite materials did not reduce vital cell numbers (P>.05) compared with the control group. Our data demonstrate that Transbond XT showed significant cytotoxicity compared with the control group. Conclusion: Results indicate that tested orthodontic bonding composites are suitable for clinical application, but that further studies using different test methods are needed for Transbond XT. (Angle Orthod. 2010;80:759-764.)en_US
dc.identifier.doi10.2319/092809-537.1
dc.identifier.endpage764en_US
dc.identifier.issn0003-3219
dc.identifier.issue4en_US
dc.identifier.pmid20482365en_US
dc.identifier.scopus2-s2.0-77953182125en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage759en_US
dc.identifier.urihttps://doi.org/10.2319/092809-537.1
dc.identifier.urihttps://hdl.handle.net/11616/95051
dc.identifier.volume80en_US
dc.identifier.wosWOS:000279218700023en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherE H Angle Education Research Foundation, Incen_US
dc.relation.ispartofAngle Orthodontisten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiocompatibilityen_US
dc.subjectLight-cured orthodontic compositesen_US
dc.subjectCytotoxicityen_US
dc.titleCytotoxic effects of orthodontic compositesen_US
dc.typeArticleen_US

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