Etiological evaluation and the role of plasma exchange treatment in tromboticmicroangiopathies: A retrospective analysis from Eastern Anatolia

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dc.contributor.authorHidayet, Emine
dc.contributor.authorErkurt, Mehmet Ali
dc.contributor.authorSarıcı, Ahmet
dc.contributor.authorBiçim, Soykan
dc.contributor.authorKuku, İrfan
dc.contributor.authorBerber, İlhami
dc.contributor.authorKaya, Emin
dc.date.accessioned2024-08-04T19:53:18Z
dc.date.available2024-08-04T19:53:18Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThe aim is this study was to make the etiological classification of patients diagnosed with TMA in our region and to statistically evaluate the effect of therapeutic plasma exchange, which we use in treatment, on laboratory recovery and mortality. In our study, between 2009-2017, 85 patients diagnosed with TMA in our center evaluated retrospectively. Thirty- one (36.5%) of our patients were followed up with HELLP, 23 with thrombotic thrombocytopenic purpura (TTP) (27.1%), 20 (23.5%) snake bites, and 11 (12.9%) with atypical hemolytic uremic syndrome (aHUS). TPE treatment was performed in all patients. TPE treatment was found effective in patients with HELLP syndrome, TTP and snake bite and statistically significant improvement was obtained in laboratory parameters (p<0.05). However, TPE treatment was not found to be effective in the treatment of atipical HUS (p>0.05). Mortality rates were found 9.7%, 21.7%, 27.3%, and 0% in patients with HELLP Syndrome, TTP, aHUS, and snake bite, respectively. The primary treatment in HELLP syndrome was termination of pregnancy, it was observed in our study that TPE was effective in TTP, HELLP syndrome and snake bites and treatment should be started without delayen_US
dc.identifier.doi10.5455/medscience.2021.11.379
dc.identifier.endpage765en_US
dc.identifier.issn2147-0634
dc.identifier.issue2en_US
dc.identifier.startpage762en_US
dc.identifier.trdizinid529831en_US
dc.identifier.urihttps://doi.org/10.5455/medscience.2021.11.379
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/529831
dc.identifier.urihttps://hdl.handle.net/11616/89670
dc.identifier.volume11en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEtiological evaluation and the role of plasma exchange treatment in tromboticmicroangiopathies: A retrospective analysis from Eastern Anatoliaen_US
dc.typeArticleen_US

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