Reference intervals of serum cystatin C for determining cystatin C-based glomerular filtration rates in preterm neonates

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dc.authoridElmas, Ahmet Taner/0000-0002-9749-6115;
dc.authorwosidElmas, Ahmet Taner/ABI-1338-2020
dc.authorwosidELMAS, Ahmet Taner/W-4101-2017
dc.authorwosidTabel, Yilmaz/AAF-9801-2020
dc.contributor.authorElmas, Ahmet Taner
dc.contributor.authorTabel, Yilmaz
dc.contributor.authorElmas, Ozlem Nalbantoglu
dc.date.accessioned2024-08-04T20:37:51Z
dc.date.available2024-08-04T20:37:51Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The aim of this study is to determine the reference values of serum Cystatin C (CysC) and CysC-based estimated glomerular filtration rate (GFR) on the 3rd and 30th day of life in comparison with serum creatinine (Cr) and Cr-based estimated GFR. Methods: This prospective study was performed on 52 preterm neonates whose gestational ages were between 28 and 34 weeks. Preterm neonates were divided into three groups according to the gestational age as follows: gestational week of 28-29 (group 1), gestational week of 30-32 (group 2) and gestational week of 33-34 (group 3). Blood samples were obtained on the 3rd and the 30th days of life. CysC was determined by particle-enhanced nephelometric immunoassay. Results: The group 1 preterm neonates have higher CysC values (1.34 +/- 0.1 mg/L) on the 3rd day of life than the group 2 (1.28 +/- 0.2 mg/L) and the group 3 (1.24 +/- 0.2 mg/L) but the differences were not significant (p > 0.05, for each). CysC values were independent of gestational age, birth weight and gender (p > 0.05, for each). No correlation was found between CysC and Cr on the 3rd day of life (p > 0.05). Conclusions: CysC is regarded as an alternative for assessing the renal function in preterm neonates.en_US
dc.identifier.doi10.3109/14767058.2013.789844
dc.identifier.endpage1478en_US
dc.identifier.issn1476-7058
dc.identifier.issn1476-4954
dc.identifier.issue15en_US
dc.identifier.pmid23528044en_US
dc.identifier.scopus2-s2.0-84884553159en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1474en_US
dc.identifier.urihttps://doi.org/10.3109/14767058.2013.789844
dc.identifier.urihttps://hdl.handle.net/11616/96217
dc.identifier.volume26en_US
dc.identifier.wosWOS:000324588200003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Maternal-Fetal & Neonatal Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPreterm neonatesen_US
dc.subjectserum creatinineen_US
dc.subjectserum creatinine-based clearanceen_US
dc.subjectserum cystatin Cen_US
dc.subjectserum cystatin C-based clearanceen_US
dc.titleReference intervals of serum cystatin C for determining cystatin C-based glomerular filtration rates in preterm neonatesen_US
dc.typeArticleen_US

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