En Genç İleri Evre Grade III Endometrium Karsinomu: Olgu Sunumu
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Dosyalar
Tarih
2011
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
İnönü Üniversitesi Tıp Fakültesi Dergisi
Erişim Hakkı
Attribution 3.0 United States
Özet
Sıklıkla posmenapozal dönemde izlenen endometrium karsinomu en sık görülen jinekolojik malignensidir. Literatürde genç endometrial karsinom vakalarının; polikistik over hastalığı zemininde gelişen diferansiye erken evre kanserler olduğu vurgulanmaktadır. Bu makalede genç yaşta izlenen, ileri evre, kötü prognozlu endometrium karsinomu vakası sunulmuştur.
Olgu Sunumu: Abortus sonrası revizyon küretaj yapılmasına rağmen vajinal kanaması devam eden 23 yaşındaki hastaya endometrial biopsi uygulanmış, patolojik inceleme sonucu Grade 3 adenokarsinom olarak gelmiştir. Yapılan operasyonda 8000 cc asit mai boşaltılmış, total abdominal histerektomi, bilateral salfingooferektomi, parsiyel omentektomi, bilateral pelvik-paraaortik lenf nodu diseksiyonu uygulanmıştır. Altı kür taksol-karboplatin kemoterapisi alan hastada operasyondan yaklaşık bir yıl sonra nüks gelişmiş, verilen kemoterapiye yanıt alınamamıştır. Hasta sepsis sebebiyle 24 yaşında kaybedilmiştir.
Sonuç: Bu makalede endometriun kanseri, hiçbir risk faktörü saptanmayan 23 yaşındaki hastada izlenmiştir. Bu hasta literatürde bizim saptadığımız en genç ileri evre grade 3 endometrium kanseri olgusudur. Risk faktörleri dışında endometrium kanseri etyopatogenezinde rol alan mekanizmaları ortaya koyacak yeni yayınlara ihtiyaç vardır.
Endometrail cancer, typically diagnosed in the postmenopausal years, is the most common gynecologic malignancy. Young women with endometrial carcinoma are considered to have a favorable prognosis with early stage, well differentiated lesions. In this report we present young patient with advanced stage endometrial adenocarcinoma who had poor prognosis. Case Report: A 23 year old female applied to the hospital because of postabortal bleeding despite revision curettage. Endometral sampling was perfomed and grade 3 endometrail adenocarcinoma was diagnosed. Athought total abdominal hysterectomy, bilateral salphingoopherectomy, pelvic-paraaortic lymphadenectomy, infracolic omentectomy and chemotherapy were performed, recurrence of the tumor was observed one year after the surgery. The patient died because of sepsis in 24 years old. Conclusion: In this report endometrial cancer was observed in 23 years old patient with no obvious risk factor. This report is the youngest advanced stage grade 3 endometrial adenocarcinoma in the literature. Further studies to evaluate the etyopathogenic mechanisms of endometrial cancer without risk factors are needed.
Endometrail cancer, typically diagnosed in the postmenopausal years, is the most common gynecologic malignancy. Young women with endometrial carcinoma are considered to have a favorable prognosis with early stage, well differentiated lesions. In this report we present young patient with advanced stage endometrial adenocarcinoma who had poor prognosis. Case Report: A 23 year old female applied to the hospital because of postabortal bleeding despite revision curettage. Endometral sampling was perfomed and grade 3 endometrail adenocarcinoma was diagnosed. Athought total abdominal hysterectomy, bilateral salphingoopherectomy, pelvic-paraaortic lymphadenectomy, infracolic omentectomy and chemotherapy were performed, recurrence of the tumor was observed one year after the surgery. The patient died because of sepsis in 24 years old. Conclusion: In this report endometrial cancer was observed in 23 years old patient with no obvious risk factor. This report is the youngest advanced stage grade 3 endometrial adenocarcinoma in the literature. Further studies to evaluate the etyopathogenic mechanisms of endometrial cancer without risk factors are needed.
Açıklama
İnönü Üniversitesi Tıp Fakültesi Dergisi 2011;18(4):269-71.
Anahtar Kelimeler
İleri Evre Endometrium Kanseri, En Genç, Advanced Stage Endometrium Cancer, Youngest
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Öztürk, Ebru ; Uğur, Mete Gürol ;Özkan, Yelda ;Aydın, Abdullah ;Balat, Özcan ;(2011) En Genç İleri Evre Grade III Endometrium Karsinomu: Olgu Sunumu,İnönü Üniversitesi Tıp Fakültesi Dergisi 2011;18(4):269-71.
