Effect of spinal anaesthesia level on the dosage of sedation

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dc.authorscopusid6603931556
dc.authorscopusid6701613323
dc.authorscopusid55666804700
dc.authorscopusid7005742798
dc.contributor.authorTurkoz A.
dc.contributor.authorTogal T.
dc.contributor.authorToprak H.I.
dc.contributor.authorErsoy O.
dc.date.accessioned2024-08-04T20:00:37Z
dc.date.available2024-08-04T20:00:37Z
dc.date.issued1999
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIt is sometimes observed that the patients under high spinal anaesthesia (T3-6) alter their wakefulness and that the patients become drowsy without sedative drugs. In these cases, the dosages of the sedative drugs should be decrease if the sedative drugs necessary. We have tested whether sensory level of T8 may affect the susceptibility to the soporific effect of sedatives. ASA grade I, 63 male patients undergoing elective lower extremity surgery were randomized to receive either spinal anaesthesia with sedation (group I), or general anesthesia with sedation (group 2). Patients in group 1 were given a subarachnoid injection of 3.5 mL hyperbaric bupivacine and those patients who had a sensory blockade level of T8 after 10 min. were divided in to three subgroups consisting ten patients (group 1a, 1b, 1c) and the patients in group II were also divided into three subgroups of ten patients (group IIa, IIb, IIc). Propofol, thiopenthone and midazolam were given until patients' sedation score achieve '3' and then stopped. In group Ia patients were given thiopenthone at the rate of 40 mg/kg/hr and in group 1c, the patients were given midazolam 1 mg intravenously, every 30 seconds. In group IIa, b, c infusion of drugs were started as stated above till the sedation score of '3' then general anaesthesia were induced. In group I and group II, the dose of propofol administered until the patients sedation score of '3' was achieved was 78±12.9 (group 1a), 83.8±11.1 mg (group IIa) p>0.05, the dose of thiopenthone was 147.5±35.4 mg (group 1b), 152.0±39.4 mg (group IIb) (p>0.05) and the dose of midazolam was 5.7±1.0 mg (group 1c), 6.4±2.2 mg (group II) (p>0.05). Although all three drugs were used less in group I than in group 2, no significant differences were observed between the groups statistically. In conclusion it is not required to reduce the amount of sedative drugs in the patients having a T8 level spinal anaesthesia.en_US
dc.identifier.endpage80en_US
dc.identifier.issn1016-5150
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0032913638en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage77en_US
dc.identifier.urihttps://hdl.handle.net/11616/90848
dc.identifier.volume27en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyonen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMidazolamen_US
dc.subjectPropofolen_US
dc.subjectSedationen_US
dc.subjectSpinal anaesthesia levelen_US
dc.subjectThiopenthoneen_US
dc.titleEffect of spinal anaesthesia level on the dosage of sedationen_US
dc.title.alternativeSpinal anestezi seviyesinin sedasyon dozuna etkisien_US
dc.typeArticleen_US

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