CNS involvement of Langerhans cell histiocytosis. Report of 23 surgically treated cases

Basit Öğe Kaydı
dc.contributor.authorBelen, D
dc.contributor.authorColak, A
dc.contributor.authorOzcan, OE
dc.date.accessioned2024-08-04T20:11:51Z
dc.date.available2024-08-04T20:11:51Z
dc.date.issued1996
dc.departmentİnönü Üniversitesien_US
dc.description.abstractWe present 23 cases of Langerhans cell histiocytosis with central nervous system (CNS) involvement. The major complaints were a mass on the cranial vault in fifteen (65 %), visual disturbance in four (16 %), polyurea-polydipsia in three (13 %), and progressive weakness in all extremities in one patient (4 %). Neurological examination revealed no abnormality in sixteen patients (70 %), cranial nerve palsy, visual field defect and optic atrophy in six (26 %) and paraparesis in one (4 %). Tumoral mass was found to be located on the cranial vault (65 %), in the suprasellar region (21 %) and in the spinal column (8 %). The cranium and spinal column were both involved in one patient. All patients underwent surgery. craniectomy with grossly total tumor excision plus cranioplasty (65 %), craniotomy with subtotal tumor excision (26 %), and vertebrectomy with grafting (13 %) were performed. The clinical, radiological and histopathological features, as well as therapeutical considerations are discussed and the pertinent literature is reviewed.en_US
dc.identifier.doi10.1007/BF00314840
dc.identifier.endpage252en_US
dc.identifier.issn0344-5607
dc.identifier.issue4en_US
dc.identifier.pmid9007888en_US
dc.identifier.scopus2-s2.0-0030471702en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage247en_US
dc.identifier.urihttps://doi.org/10.1007/BF00314840
dc.identifier.urihttps://hdl.handle.net/11616/93047
dc.identifier.volume19en_US
dc.identifier.wosWOS:A1996WD40000008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter & Coen_US
dc.relation.ispartofNeurosurgical Reviewen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectbrainen_US
dc.subjecteosinophilic granulomaen_US
dc.subjectLangerhans cell histiocytosisen_US
dc.subjectspinal corden_US
dc.titleCNS involvement of Langerhans cell histiocytosis. Report of 23 surgically treated casesen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu