The Association of Serum Vitamin D Levels with Pseudoexfoliation Glaucoma/Syndrome

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dc.authoridOzturk, Emrah/0000-0002-3590-3213
dc.authorwosidÖztürk, Emrah/H-5241-2017
dc.authorwosiddikci, seyhan/A-3311-2019
dc.contributor.authorSeyhan, Dikci
dc.contributor.authorEmrah, Ozturk
dc.contributor.authorGul, Firat P.
dc.contributor.authorTurgut, Yilmaz
dc.contributor.authorCagatay, Taskapan M.
dc.contributor.authorSaim, Yologlu
dc.date.accessioned2024-08-04T20:45:44Z
dc.date.available2024-08-04T20:45:44Z
dc.date.issued2019
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: To investigate whether serum vitamin D levels have an effect on pseudoexfoliation (PEX) glaucoma/syndrome development and on the control of glaucoma in these cases. Method: A total of 31 cases with PEX glaucoma, 34 cases with the PEX syndrome and 43 control subjects of similar age and sex were included in the study. Vitamin D levels were compared between the groups and also between the cases where glaucoma surgery was performed or not. Results: PEX glaucoma group consisted of 17 males and 14 females, PEX syndrome group of 27 males and 7 females, and the control group of 27 males and 16 females. The mean age was 70.9 +/- 8.9 years, 72.1 +/- 7.3 years, and 67.9 +/- 9.1 years in PEX glaucoma, syndrome and control group, respectively. Mean vitamin D levels were 9.4 +/- 7.7 ng/mL, 7.9 +/- 6,1 ng/mL, 11.5 +/- 14.2 ng/mL in PEX glaucoma, syndrome and control group, respectively (p>0.05). The mean serum vitamin D level was 8.04 +/- 4.7 ng/mL in those who underwent glaucoma surgery and 10.1 +/- 8.7 ng/mL in those who didn't undergo glaucoma surgery in PEX glaucoma group (p>0.05). No difference was found between the PEX glaucoma subgroups in terms of the mean deviation when classified according to vitamin D levels (<10 ng/mL, >= 10 ng/mL) (p>0.05). Conclusion: Although we found no statistically significant difference between the PEX syndrome/glaucoma, and control group in terms of serum vitamin D levels, serum vitamin D levels were lower in PEX syndrome and glaucoma group than control group. Our results indicate that serum vitamin D levels have no effect on the development of PEX glaucoma/syndrome or the control of the disorder in cases with PEX glaucoma. However, these results need to be supported with further studies on a larger number of patients and with longer follow-up.en_US
dc.description.sponsorshipInonu University Scientific Research Projects Coordination Unit [2016/59]en_US
dc.description.sponsorshipThe study was supported by the Inonu University Scientific Research Projects Coordination Unit (The Researches' Grand number of the study is 2016/59).en_US
dc.identifier.doi10.2174/1871530319666181128105911
dc.identifier.endpage170en_US
dc.identifier.issn1871-5303
dc.identifier.issn2212-3873
dc.identifier.issue2en_US
dc.identifier.pmid30484415en_US
dc.identifier.scopus2-s2.0-85061874618en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage166en_US
dc.identifier.urihttps://doi.org/10.2174/1871530319666181128105911
dc.identifier.urihttps://hdl.handle.net/11616/98662
dc.identifier.volume19en_US
dc.identifier.wosWOS:000458025000009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBentham Science Publ Ltden_US
dc.relation.ispartofEndocrine Metabolic & Immune Disorders-Drug Targetsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlaucomaen_US
dc.subjectpseudoexfoliationen_US
dc.subjectpseudoexfoliation glaucomaen_US
dc.subjectpseudoexfoliation syndromeen_US
dc.subjectvitamin Den_US
dc.subject1,25 dihydroxyvitamin Den_US
dc.titleThe Association of Serum Vitamin D Levels with Pseudoexfoliation Glaucoma/Syndromeen_US
dc.typeArticleen_US

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