Toxoplasma gondii - obsessive -compulsive disorder relationship: is it different in children?

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dc.authoridÖzcan, Özlem/0000-0003-3267-2648
dc.authoridUnal, Suheyla/0000-0003-3266-6256
dc.authoridUnal, Suheyla/0000-0003-3266-6256
dc.authorwosidÖzcan, Özlem/ABH-9167-2020
dc.authorwosidUnal, Suheyla/HJH-7559-2023
dc.authorwosidUnal, Suheyla/JVO-8367-2024
dc.contributor.authorMiman, Ozlem
dc.contributor.authorOzcan, Ozlem
dc.contributor.authorUnal, Sueheyla
dc.contributor.authorAtambay, Metin
dc.date.accessioned2024-08-04T20:45:31Z
dc.date.available2024-08-04T20:45:31Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground and aim: Obsessive-compulsive disorder (OCD) is a common neuropsychiatric illness. Although the etiology of OCD is still unknown, recent investigations have associated development of OCD with infectious illness. Toxoplasma gondii (T. gondii) is a neurotropic protozoan parasite that causes infection of the central nervous system. In the last decade, a lot of researches have focused on the possible relationship between exposure to T. gondii and neuropsychiatric disorders such as schizophrenia. Therefore, in this study, it was aimed to investigate a possible association between Toxoplasma infection and OCD in children and adolescents.Methods: We selected 55 patients with OCD (aged between 7 and 16 years) and 59 healthy children and adolescents (aged between 7 and 16 years), and investigated the seropositivity rate for anti-Toxoplasma IgG antibodies by enzyme-linked immunosorbent assay.Results: The seropositivity rate for anti-T. gondii IgG antibodies among OCD patients (21.82%) was found to be higher than the rate in control group (15.25%). However, the difference between the OCD group and the control group was not statistically significant (p>.05).Conclusion: In contrast to studies in adult patients, the results of this study do not support the relationship between T. gondii and OCD children and adolescents.en_US
dc.identifier.doi10.1080/08039488.2018.1514421
dc.identifier.endpage505en_US
dc.identifier.issn0803-9488
dc.identifier.issn1502-4725
dc.identifier.issue7en_US
dc.identifier.pmid30383476en_US
dc.identifier.scopus2-s2.0-85056080295en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage501en_US
dc.identifier.urihttps://doi.org/10.1080/08039488.2018.1514421
dc.identifier.urihttps://hdl.handle.net/11616/98525
dc.identifier.volume72en_US
dc.identifier.wosWOS:000456435500008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofNordic Journal of Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdolescenten_US
dc.subjectchilden_US
dc.subjectenzyme-linked immunosorbent assayen_US
dc.subjectobsessive-compulsive disorderen_US
dc.subjectToxoplasmaen_US
dc.titleToxoplasma gondii - obsessive -compulsive disorder relationship: is it different in children?en_US
dc.typeArticleen_US

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