Comparison of the effects of dexmedetomidineremifentanil and propofol-remifentanil combinations on postoperative cognitive functions in patients undergoing hysteroscopy: A randomized prospective study
Yükleniyor...
Dosyalar
Tarih
2019
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: In the present study, we aimed to compare Dexmedetomidine-Remifentanil and Propofol-Remifentanil combinations in terms
of postoperative cognitive functions in hysteroscopy attempts.
Material and Methods: A total of 70 ASA I-II patients who were aged between 18 and 65 years were included in the study following
the ethics committee approval. The patients were randomized into two groups (n=35), and standard routine monitoring were applied
to them. The sedation depth was evaluated with Ramsey Sedation Score (RSS) before and after the sedation; and cognitive functions
of the groups were evaluated with the Minimal Mental State Test (MMST).
Propofol 1 mg/kg bolus 25-100 µg/kg/min infusion was administered to Group PR, and Dexmedetomidine 1 µg/kg bolus 0.4-0.7 µg/
kg/h infusion dose was administered to Group DR. Remifentanil 0.25 µg/kg bolus 0.04 µg /kg/min infusion was administered to the
groups, and the groups were followed to ensure RSS≥4.
Result: In cognitive functions, it was observed that there was significant regression in Group PR in postoperative period compared
to the preoperative period (p<0.05). The hemodynamic parameters were lower in Group DR than in Group PR at 5th, 10th and 15th
minutes following the hysteroscopy (p<0.05). The Modified Aldrete Score in Group DR were high, and pain scores were lower (p<0.05).
Satisfaction with the surgeon, patient and anesthetist scores were higher in Group DR. No respiratory depression was observed
(p<0.05).
Conclusion: We believe that administering Dexmedetomidine-Remifentanil combination in sedation in hysteroscopy ensures better
postoperative cognitive function, recovery conditions, analgesia, and patient and surgeon satisfaction compared to the PropofolRemifentanil combination.
Açıklama
Anahtar Kelimeler
Kaynak
Annals of Medical Research
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Atasoy, I., Soyalp, C., & Gulhas, N. (2021). Comparison of the effects of dexmedetomidineremifentanil and propofol-remifentanil combinations on postoperative cognitive functions in patients undergoing hysteroscopy: A randomized prospective study . Annals of Medical Research
