Therapeutic potential of coumarin bearing metal complexes: Where are we headed?

Küçük Resim Yok

Tarih

2020

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Pergamon-Elsevier Science Ltd

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The successfully application of some metallodrugs such as salvarsan, silver sulfadiazine and cisplatin in modern medicine launched the biological investigation of organometallic and metal-organic complexes. The availability and tunability of various ligands including N-heterocycles, phosphines, N-heterocyclic carbenes present an extended research area to chemists. In recent years, the preparation of the metal complexes of bioactive organic compounds is a new strategy. Coumarin derivatives are one of the classes of compounds used for this purpose, and many complexes of coumarin derivatives were prepared for enhanced biological activity, especially anticancer and antimicrobial. In this paper, we discuss the current situation of this topic.

Açıklama

Anahtar Kelimeler

Coumarin derivatives, Metal complexes, Anticancer, Antimicrobial, Biological activity

Kaynak

Bioorganic & Medicinal Chemistry Letters

WoS Q Değeri

Q2

Scopus Q Değeri

Q2

Cilt

30

Sayı

2

Künye